Molybdenum Disulfide Surface Modification of Ultrafine-Grained Titanium for Enhanced Cellular Growth and Antibacterial Effect
SCIE
SCOPUS
- Title
- Molybdenum Disulfide Surface Modification of Ultrafine-Grained Titanium for Enhanced Cellular Growth and Antibacterial Effect
- Authors
- Shin, Myeong Hwan; Baek, Seung Mi; Polyakov, Alexander V.; Semenova, Irina P.; Valiev, Ruslan Z.; Hwang, Woon-bong; Hahn, Sei Kwang; Kim, Hyoung Seop
- Date Issued
- 2018-07
- Publisher
- NATURE PUBLISHING GROUP
- Abstract
- The commercially pure Ti (CP Ti) and equal-channel angular pressing (ECAP) processed Ti can contribute to the downsizing of medical devices with their superior mechanical properties and negligible toxicity. However, the ECAP-processed pure Ti has the risk of bacterial infection. Here, the coarse-and ultrafinegrained Ti substrates were surface-modified with molybdenum disulfide (MoS2) to improve the cell proliferation and growth with antibacterial effect for further dental applications. According to in vitro tests using the pre-osteoblast of MC3T3-E1 cell and a bacterial model of Escherichia coli (E. coli), MoS2 nanoflakes coated and ECAP-processed Ti substrates showed a significant increase in surface energy and singlet oxygen generation resulting in improved cell attachment and antibacterial effect. In addition, we confirmed the stability of the surface modified Ti substrates in a physiological solution and an artificial bone. Taken together, MoS2 modified and ECAP-processed Ti substrates might be successfully harnessed for various dental applications.
- URI
- https://oasis.postech.ac.kr/handle/2014.oak/94289
- DOI
- 10.1038/s41598-018-28367-0
- ISSN
- 2045-2322
- Article Type
- Article
- Citation
- Scientific Reports, vol. 8, no. 1, 2018-07
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- There are no files associated with this item.
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