Copper-Catalyzed Diastereoselective and Enantioselective Addition of 1,1-Diborylalkanes to Cyclic Ketimines and alpha-Imino Esters
SCIE
SCOPUS
- Title
- Copper-Catalyzed Diastereoselective and Enantioselective Addition of 1,1-Diborylalkanes to Cyclic Ketimines and alpha-Imino Esters
- Authors
- KIM, JUNG HO; SHIN, MINKYEONG; CHO, SEUNG HWAN
- Date Issued
- 2019-08
- Publisher
- AMER CHEMICAL SOC
- Abstract
- We report broadly applicable copper catalytic conditions for the diastereoselective and enantioselective 1,2-addition of 1,1-diborylalkanes to cyclic ketimines and alpha-imino esters. The developed method provides various beta-aminoboronate esters bearing adjacent stereocenters with high diastereo- and enantioselectivity. Synthetic applications for converting the obtained beta-aminoboronate esters to a diverse array of synthetically useful chiral compounds are demonstrated.
- URI
- https://oasis.postech.ac.kr/handle/2014.oak/99696
- DOI
- 10.1021/acscatal.9b02931
- ISSN
- 2155-5435
- Article Type
- Article
- Citation
- ACS CATALYSIS, vol. 9, no. 9, page. 8503 - 8508, 2019-08
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