Generation and Application of (Diborylmethyl)zinc(II) Species: Access to Enantioenriched gem-Diborylalkanes by an Asymmetric Allylic Substitution
SCOPUS
- Title
- Generation and Application of (Diborylmethyl)zinc(II) Species: Access to Enantioenriched gem-Diborylalkanes by an Asymmetric Allylic Substitution
- Authors
- YEOSAN, LEE; PARK, JIN YOUNG; CHO, SEUNG HWAN
- Date Issued
- 2018-09
- Publisher
- WILEY-V C H VERLAG GMBH
- Abstract
- We report the successful generation of (diborylmethyl)zinc(II) species by transmetallation beteween isolable (diborylmethyl)lithium and zinc(II) halide (X=Br, Cl) and their application in the synthesis of enantioenriched gem‐diborylalkanes bearing a stereogenic center at the β‐position of the diboryl groups by an asymmetric allylic substitution reaction. The reaction has a broad substrate scope, and various enantioenriched gem‐diborylalkanes can be obtained in good yields with excellent enantioselectivity. Further elaboration of the enantioenriched gem‐diborylalkanes provides access to a diverse set of valuable chiral building blocks.
- URI
- https://oasis.postech.ac.kr/handle/2014.oak/93982
- DOI
- 10.1002/anie.201805476
- ISSN
- 1433-7851
- Article Type
- Article
- Citation
- ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, vol. 57, no. 39, page. 12930 - 12934, 2018-09
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