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Nitric oxide-activatable gold nanoparticles for specific targeting and photo-thermal ablation of macrophages SCIE SCOPUS

Title
Nitric oxide-activatable gold nanoparticles for specific targeting and photo-thermal ablation of macrophages
Authors
Park, JunghongPramanick, SwapanKim, JinhwanLee, JihyunKim, Won Jong
Date Issued
2017-10
Publisher
ROYAL SOC CHEMISTRY
Abstract
In this study, we designed NO-activatable gold nanoparticles (NAM-AuNPs) for specific targeting and photo-thermal ablation of macrophages. The gold nanoparticles showed aggregation behavior in response to NO solution as well as endogenous NO secreted from activated macrophages. Following NIR irradiation, significant cytotoxicity was observed in activated RAW 264.7 cells treated with NAM-AuNPs.
Keywords
THERAPY; ATHEROSCLEROSIS; INFLAMMATION; CELLS
URI
https://oasis.postech.ac.kr/handle/2014.oak/92005
DOI
10.1039/c7cc06420a
ISSN
1359-7345
Article Type
Article
Citation
CHEMICAL COMMUNICATIONS, vol. 53, no. 81, page. 11229 - 11232, 2017-10
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김원종KIM, WON JONG
Dept of Chemistry
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