Nitric oxide-activatable gold nanoparticles for specific targeting and photo-thermal ablation of macrophages
SCIE
SCOPUS
- Title
- Nitric oxide-activatable gold nanoparticles for specific targeting and photo-thermal ablation of macrophages
- Authors
- Park, Junghong; Pramanick, Swapan; Kim, Jinhwan; Lee, Jihyun; Kim, Won Jong
- Date Issued
- 2017-10
- Publisher
- ROYAL SOC CHEMISTRY
- Abstract
- In this study, we designed NO-activatable gold nanoparticles (NAM-AuNPs) for specific targeting and photo-thermal ablation of macrophages. The gold nanoparticles showed aggregation behavior in response to NO solution as well as endogenous NO secreted from activated macrophages. Following NIR irradiation, significant cytotoxicity was observed in activated RAW 264.7 cells treated with NAM-AuNPs.
- Keywords
- THERAPY; ATHEROSCLEROSIS; INFLAMMATION; CELLS
- URI
- https://oasis.postech.ac.kr/handle/2014.oak/92005
- DOI
- 10.1039/c7cc06420a
- ISSN
- 1359-7345
- Article Type
- Article
- Citation
- CHEMICAL COMMUNICATIONS, vol. 53, no. 81, page. 11229 - 11232, 2017-10
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- There are no files associated with this item.
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