A novel bacteriochlorin-gold nanoparticle construct for photoacoustic imaging
SCIE
SCOPUS
- Title
- A novel bacteriochlorin-gold nanoparticle construct for photoacoustic imaging
- Authors
- Srivatsan, Avinash; Jeon, Mansik; Wang, Yanfang; Chen, Yihui; Kim, Chulhong; Pandey, Ravindra K.
- Date Issued
- 2016-01
- Publisher
- WORLD SCI PUBL CO INC
- Abstract
- Herein we report the synthesis of new gold nanoparticle-bacteriochlorin conjugate (Au-NP-PS) as a highly efficient photoacoustic (PA) imaging agent. The conjugate was obtained by reacting a water soluble thio-bacteriochlorin (derived from bacteriochlorophyll-a) with Au-NP. The resulting NPs were characterized by UV-vis, TEM (transmission electron microscopy)/HRTEM (high resolution TEM) and diffraction pattern. The results obtained from in vitro studies suggest that due to conjugation between the PS and Au-NPs, the photoacoustic (PA) signals from the Au-NP-PS were greatly enhanced by a factor of 2.4 compared to that from PS alone.
- Keywords
- SURFACE-PLASMON RESONANCE; CONTRAST AGENTS; TOMOGRAPHY; SYSTEM; NAPHTHALOCYANINES; NANOCAGES; THERAPY
- URI
- https://oasis.postech.ac.kr/handle/2014.oak/50584
- DOI
- 10.1142/S1088424616500358
- ISSN
- 1088-4246
- Article Type
- Article
- Citation
- JOURNAL OF PORPHYRINS AND PHTHALOCYANINES, vol. 20, no. 1, page. 490 - 496, 2016-01
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