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Identification of Cancer Cell-Line Origins Using Fluorescence Image-Based Phenomic Screening SCIE SCOPUS
- Title
- Identification of Cancer Cell-Line Origins Using Fluorescence Image-Based Phenomic Screening
- Authors
- Lee, Jun-Seok; Kim, Yun Kyung; Kim, Han Jo; Hajar, Siti; Tan, Yee Ling; Kang, Nam-Young; Ng, Shin Hui; Yoon, Chang No; Chang, Young-Tae
- Date Issued
- 2012-02
- Publisher
- PUBLIC LIBRARY SCIENCE
- Abstract
- Universal phenotyping techniques that can discriminate among various states of biological systems have great potential. We applied 557 fluorescent library compounds to NCI's 60 human cancer cell-lines (NCI-60) to generate a systematic fluorescence phenotypic profiling data. By the kinetic fluorescence intensity analysis, we successfully discriminated the organ origin of all the 60 cell-lines.
- Keywords
- PHENOTYPES; MOLECULES; PATTERNS; LIBRARY; CONTEXT; PROBE
- ISSN
- 1932-6203
- Article Type
- Article
- Citation
- PLOS ONE, vol. 7, no. 2, 2012-02
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