Diastereo- and Enantioselective Synthesis of β-Aminoboronate Esters by Copper(I)-Catalyzed 1,2-Addition of 1,1-Bis[(pinacolato)boryl]alkanes to Imines
SCIE
SCOPUS
- Title
- Diastereo- and Enantioselective Synthesis of β-Aminoboronate Esters by Copper(I)-Catalyzed 1,2-Addition of 1,1-Bis[(pinacolato)boryl]alkanes to Imines
- Authors
- KIM, JEOUNGHO; KO, KWANGWOOK; CHO, SEUNG HWAN
- Date Issued
- 2017-09
- Publisher
- Wiley
- Abstract
- Reported herein is an efficient copper(I)-catalyticsystem for the diastereo- and enantioselective 1,2-addition of1,1-bis[(pinacolato)boryl]alkanes to protected imines to affordsynthetically valuable enantioenriched b-aminoboron com-pounds bearing contiguous stereogenic centers.The reactionexhibits abroad scope with respect to protected imines and 1,1-bis[(pinacolato)boryl]alkanes,thus providing b-aminoboro-nate esters with excellent diastereo- and enantioselectivity.Thesynthetic utility of the obtained b-aminoboronate ester was alsodemonstrated.
- URI
- https://oasis.postech.ac.kr/handle/2014.oak/39029
- DOI
- 10.1002/anie.201705829
- ISSN
- 1433-7851
- Article Type
- Article
- Citation
- Angewandte Chemie International Edition, vol. 56, no. 38, page. 11584 - 11588, 2017-09
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- There are no files associated with this item.
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