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Hyaluronate-Flt1 peptide conjugate/epirubicin micelles for theranostic application to liver cancers SCIE SCOPUS
- Title
- Hyaluronate-Flt1 peptide conjugate/epirubicin micelles for theranostic application to liver cancers
- Date Issued
- 2015-05
- Publisher
- ROYAL SOC CHEMISTRY
- Abstract
- Cancer theranostic systems using polymeric micelles are emerging for simultaneous diagnosis and therapy. In this work, we have developed hyaluronate (HA)-Flt1 peptide conjugate micelles encapsulating epirubicin for theranostic treatment of hepatocellular carcinoma. Intravital bioimaging without labelling and in vivo anti-tumor therapeutic effect clearly confirmed the feasibility of HA-Flt1 peptide conjugate/epirubicin micelles for target-specific theranostic treatment of liver cancers.
- Keywords
- HYALURONIC-ACID DERIVATIVES; DRUG-DELIVERY SYSTEMS; POLYMERIC MICELLES; ANTI-FLT1 PEPTIDE; CONJUGATE; DOXORUBICIN; NEOVASCULARIZATION; NANOPARTICLES; EPIRUBICIN; RECEPTOR
- ISSN
- 2046-2069
- Article Type
- Article
- Citation
- RSC ADVANCES, vol. 5, no. 60, page. 48615 - 48618, 2015-05
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