Fast racemization and dynamic kinetic resolution of primary benzyl amines
SCIE
SCOPUS
- Title
- Fast racemization and dynamic kinetic resolution of primary benzyl amines
- Authors
- Kim, Y; Park, J; Kim, MJ
- Date Issued
- 2010-10-20
- Publisher
- PERGAMON-ELSEVIER SCIENCE LTD
- Abstract
- We prepared a Pd nanocatalyst (average diameter of Pd nanoparticles = 1.73 nm) displaying a remarkable activity for the racemization and dynamic kinetic resolution (DKR) of 1-methylbenzylamine. It was eight times more active than the previous best. The DKR of 1-methylbenzylamine with the Pd nanocatalyst (2 mol %) in the presence of a thermostable lipase (Novozym 435) was complete in 6 h at 70 degrees C. The DKRs of other benzyl amines also proceeded to completion in 6 h under similar conditions except the amount of Pd nanocatalyst. (C) 2010 Elsevier Ltd. All rights reserved.
- Keywords
- RADICAL-MEDIATED RACEMIZATION; ENANTIOMERICALLY PURE AMINES; ASYMMETRIC TRANSFORMATIONS; AMBIENT-TEMPERATURE; SECONDARY ALCOHOLS; CATALYTIC RACEMIZATION; CHIRAL AMINES; METAL; EFFICIENT; ENZYMES
- URI
- https://oasis.postech.ac.kr/handle/2014.oak/25535
- DOI
- 10.1016/J.TETLET.2010.08.050
- ISSN
- 0040-4039
- Article Type
- Article
- Citation
- TETRAHEDRON LETTERS, vol. 51, no. 42, page. 5581 - 5584, 2010-10-20
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- There are no files associated with this item.
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