Structure-activity relationship studies of the chromosome segregation inhibitor, Incentrom A
SCIE
SCOPUS
- Title
- Structure-activity relationship studies of the chromosome segregation inhibitor, Incentrom A
- Authors
- Lee, HY; Jung, Y; Kim, W; Jin, HKB; Suh, MS; Shin, SK; Yoon, HJ
- Date Issued
- 2008-08-15
- Publisher
- PERGAMON-ELSEVIER SCIENCE LTD
- Abstract
- A series of Incentrom A analogs that inhibit the chromosome segregation process in yeast were synthesized and tested for their effects on chromosome stability and cell proliferation. Pharmacophore and structure-activity relationship of Incentrom A for the anti-yeast activity were established. (C) 2008 Elsevier Ltd. All rights reserved.
- Keywords
- inhibition; chromosome segregation; yeast; structure-activity relationship; pharmacophore; incentrom A; CENTROMERE
- URI
- https://oasis.postech.ac.kr/handle/2014.oak/22541
- DOI
- 10.1016/J.BMCL.2008.07.006
- ISSN
- 0960-894X
- Article Type
- Article
- Citation
- BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 18, no. 16, page. 4670 - 4674, 2008-08-15
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- There are no files associated with this item.
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