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Synthesis of 1,4-dideoxy-1,4-imino-D-arabinitol (D-AB1) through a divergent approach SCIE SCOPUS
- Title
- Synthesis of 1,4-dideoxy-1,4-imino-D-arabinitol (D-AB1) through a divergent approach
- Date Issued
- 1997-11-20
- Publisher
- KOREAN CHEMICAL SOC
- Abstract
- A divergent approach to 2-(hydroxymethyl)pyrrolidine-3,4-diols has been studied with 1,4-dideoxy-1,4-imino-D-arabinitol (D-AB1), a potent glycosidase inhibitor. D-AB1 was efficiently synthesized from 2,3-epoxyalcohol 6a in overall 11% yield.
- Keywords
- 2,3-EPOXY ALCOHOLS; DERIVATIVES; INHIBITORS; 1,4-DIDEOXY-1,4-IMINO-L-ARABINITOL; FAGOMINE; (2R; 4R)-2-HYDROXYMETHYL-3,4-DIHYDROXYPYRROLIDINE; 1-DEOXYMANNOJIRIMYCIN; 1-DEOXYNOJIRIMYCIN; ENANTIOMERS
- ISSN
- 0253-2964
- Article Type
- Article
- Citation
- BULLETIN OF THE KOREAN CHEMICAL SOCIETY, vol. 18, no. 11, page. 1192 - 1195, 1997-11-20
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Related Researcher
- 안교한AHN, KYO HAN
- Dept of Chemistry