Enzymatic selective dehydration and skeleton rearrangement of paclitaxel precursors
SCIE
SCOPUS
- Title
- Enzymatic selective dehydration and skeleton rearrangement of paclitaxel precursors
- Authors
- Lee, D; Kim, MJ
- Date Issued
- 1999-09-23
- Publisher
- AMER CHEMICAL SOC
- Abstract
- [GRAPHICS] Enzymatic dehydration reactions to remove selectively the chemically least reactive 13-hydroxyl group of 10-deacetylbaccatin III and its derivatives 2a-c are described. The elimination of the 13-OH takes place with skeleton rearrangement, allowing us to synthesize some interesting diterpenoids in good yields.
- Keywords
- BACCATIN-III; 10-DEACETYL BACCATIN; TAXOL; 10-DEACETYLBACCATIN-III; ACYLATION
- URI
- https://oasis.postech.ac.kr/handle/2014.oak/20128
- DOI
- 10.1021/ol990179m
- ISSN
- 1523-7060
- Article Type
- Article
- Citation
- ORGANIC LETTERS, vol. 1, no. 6, page. 925 - 927, 1999-09-23
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- There are no files associated with this item.
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