Novel thermoreversible gelation of biodegradable PLGA-block-PEO-block-PLGA triblock copolymers in aqueous solution
SCIE
SCOPUS
- Title
- Novel thermoreversible gelation of biodegradable PLGA-block-PEO-block-PLGA triblock copolymers in aqueous solution
- Authors
- Lee, DS; Shim, MS; Kim, SW; Lee, H; Park, I; Chang, TY
- Date Issued
- 2001-06-15
- Publisher
- WILEY-V C H VERLAG GMBH
- Abstract
- The BAB-type triblock copolymers composed of a central poly(ethylene oxide) (PEO, (M) over bar (nPEO) = 1000) block and two poly[(D,L-lactic acid)-co(glycolic acid)] end blocks with molecular weights between 900 and 1600 exhibited an interesting phase transition behaviour. The copolymer aqueous solution can form micelles with PLGA loops in the core and a PEO shell and groups of micelles because of bridging between micelles caused by the PLGA blocks with raising temperature. A possible micellar gelation mechanism was suggested.
- Keywords
- ETHYLENE-OXIDE; ASSOCIATION; BEHAVIOR
- URI
- https://oasis.postech.ac.kr/handle/2014.oak/19496
- DOI
- 10.1002/1521-3927(20010501)22:8<587::AID-MARC587>3.0.CO;2-8
- ISSN
- 1022-1336
- Article Type
- Article
- Citation
- MACROMOLECULAR RAPID COMMUNICATIONS, vol. 22, no. 8, page. 587 - 592, 2001-06-15
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- There are no files associated with this item.
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