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A short and efficient stereoselective synthesis of all four diastereomers of sphingosine SCIE SCOPUS

Title
A short and efficient stereoselective synthesis of all four diastereomers of sphingosine
Authors
Lee, JMLim, HSChung, SK
Date Issued
2002-03-22
Publisher
PERGAMON-ELSEVIER SCIENCE LTD
Abstract
Practical syntheses of all four stereomers of sphingosine from serine have been achieved through highly diastereoselective reduction of the N-trityl protected alpha'-amino enone derivative 5 with NaBH4 and reduction of the free alpha'-amino enone derivative 7 with Zn(BH4)(2). (C) 2002 Elsevier Science Ltd. All rights reserved.
Keywords
D-ERYTHRO-SPHINGOSINE; BETA-AMINO ALCOHOLS; L-THREO-SPHINGOSINE; LIPID 2ND-MESSENGERS; EMMONS REACTION; CELL-ADHESION; L-SERINE
URI
https://oasis.postech.ac.kr/handle/2014.oak/19090
DOI
10.1016/S0957-4166(02)00118-0
ISSN
0957-4166
Article Type
Article
Citation
TETRAHEDRON-ASYMMETRY, vol. 13, no. 4, page. 343 - 347, 2002-03-22
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