Quencher-free linear beacon systems containing 2-ethynylfluorenone-labeled 2’-deoxyuridine units
SCIE
SCOPUS
- Title
- Quencher-free linear beacon systems containing 2-ethynylfluorenone-labeled 2’-deoxyuridine units
- Authors
- Ryu, JH; Heo, JY; Bang, EK; Hwang, GT; Kim, BH
- Date Issued
- 2012-01-07
- Publisher
- PERGAMON-ELSEVIER SCIENCE LTD
- Abstract
- In this study we synthesized the 2-ethynylfluorenone-containing deoxyuridine derivative U-FO and incorporated it at the central positions of oligodeoxynucleotides (ODNs) in an attempt to develop a new type of quencher-free linear beacon probe and to understand the effect of functionalization of the fluorene scaffold on the photophysical properties of the fluorescent ODNs. Herein, we describe our photophysical studies of UFO DNA probes and their application to single-nucleotide polymorphism typing. (C) 2011 Elsevier Ltd. All rights reserved.
- Keywords
- Fluorenone; Oligonucleotides; Fluorescence; Single-nucleotide polymorphism; DNA probe; SINGLE-BASE MISMATCHES; MOLECULAR BEACONS; DNA; FLUORESCENCE; PROBES; DUPLEX; FLUOROPHORES; FLUORENONE; ENERGY
- URI
- https://oasis.postech.ac.kr/handle/2014.oak/16984
- DOI
- 10.1016/J.TET.2011.10.092
- ISSN
- 0040-4020
- Article Type
- Article
- Citation
- TETRAHEDRON LETTERS, vol. 68, no. 1, page. 72 - 78, 2012-01-07
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- There are no files associated with this item.
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