Selective Fluorescent Detection of RNA in Living Cells by Using Imidazolium-Based Cyclophane
SCIE
SCOPUS
- Title
- Selective Fluorescent Detection of RNA in Living Cells by Using Imidazolium-Based Cyclophane
- Authors
- Bahareh Shirinfar; Nisar Ahmed; Yu Shin Park; Gun-Sik Cho; Il Seung Youn; Han, JK; Hong Gil Nam; Kim, KS
- Date Issued
- 2013-01-09
- Publisher
- American Chemical Society
- Abstract
- A water-soluble imidazolium-based fluorescent chemosensor senses RNA selectively through fluorescence enhancement over other biologically relevant biomolecules in aqueous solution at physiological pH 7.4. Fluorescence image detection of RNA in living cells such as onion cells, HeLa cells, and animal model cells was successfully demonstrated which displays a chelation-enhanced fluorescence effect. These affinities can be attributed to the strong electrostatic (C-H)(+)center dot center dot center dot A(-) ionic H-bonding and the aromatic moiety driven pi-stacking of imidazolium-based cyclophane with the size-complementary major groove of RNA.
- URI
- https://oasis.postech.ac.kr/handle/2014.oak/14847
- DOI
- 10.1021/JA3112274
- ISSN
- 0002-7863
- Article Type
- Article
- Citation
- JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, vol. 135, no. 1, page. 90 - 93, 2013-01-09
- Files in This Item:
- There are no files associated with this item.
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.