Synthesis of condensed pyrroloindoles via Pd-catalyzed intramolecular C-H bond functionalization of pyrroles
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SCOPUS
- Title
- Synthesis of condensed pyrroloindoles via Pd-catalyzed intramolecular C-H bond functionalization of pyrroles
- Authors
- HWANG, SEUNG JUN; Cho, SH; Chang, S
- Date Issued
- 2008-12-03
- Publisher
- American Chemical Society
- Abstract
- A new strategy for the synthesis of condensed hetero- or carbocycles such as pyrroloindoles or fluorenes has been developed that involves the Pd-catalyzed cyclization of readily available N-(2-halobenzyl)pyrroles or their phenyl derivatives. The reaction is proposed to proceed via oxidative addition of benzylic halides to Pd(0) followed by base-assisted C-H bond activation. A broad range of condensed cyclic products could be obtained in good to excellent yields under mild conditions.
- URI
- https://oasis.postech.ac.kr/handle/2014.oak/14430
- DOI
- 10.1021/JA806897H
- ISSN
- 0002-7863
- Article Type
- Article
- Citation
- JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, vol. 130, no. 48, page. 16158 - 16159, 2008-12-03
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