The disassembly of lipid droplets in Chlamydomonas
SCIE
SCOPUS
- Title
- The disassembly of lipid droplets in Chlamydomonas
- Authors
- Li-Beisson, Y.; Kong, F.; Wang, P.; LEE, YOUNGSOOK; Kang, B.-H.
- Date Issued
- 2021-08
- Publisher
- Blackwell Publishing Inc.
- Abstract
- Lipid droplets (LDs) are ubiquitous and specialized organelles in eukaryotic cells. Consisting of a triacylglycerol core surrounded by a monolayer of membrane lipids, LDs are decorated with proteins and have myriad functions, from carbon/energy storage to membrane lipid remodeling and signal transduction. The biogenesis and turnover of LDs are therefore tightly coordinated with cellular metabolic needs in a fluctuating environment. Lipid droplet turnover requires remodeling of the protein coat, lipolysis, autophagy and fatty acid beta-oxidation. Several key components of these processes have been identified in Chlamydomonas (Chlamydomonas reinhardtii), including the major lipid droplet protein, a CXC-domain containing regulatory protein, the phosphatidylethanolamine-binding DTH1 (DELAYED IN TAG HYDROLYSIS1), two lipases and two enzymes involved in fatty acid beta-oxidation. Here, we review LD turnover and discuss its physiological significance in Chlamydomonas, a major model green microalga in research on algal oil.
- URI
- https://oasis.postech.ac.kr/handle/2014.oak/108483
- DOI
- 10.1111/nph.17505
- ISSN
- 0028-646X
- Article Type
- Article
- Citation
- New Phytologist, vol. 231, no. 4, page. 1359 - 1364, 2021-08
- Files in This Item:
- There are no files associated with this item.
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.