A photoacoustic finder fully integrated with a solid-state dye laser and transparent ultrasound transducer
SCIE
SCOPUS
- Title
- A photoacoustic finder fully integrated with a solid-state dye laser and transparent ultrasound transducer
- Authors
- PARK, BYULLEE; Han, Moongyu; JEONGWOO, PARK; 김태정; Ryu, Hanyoung; Seo, Youngseok; KIM, WON JONG; Kim, Hyung Ham; KIM, CHULHONG
- Date Issued
- 2021-09
- Publisher
- Elsevier BV
- Abstract
- The standard-of-care for evaluating lymph node status in breast cancers and melanoma metastasis is sentinel lymph node (SLN) assessment performed with a handheld gamma probe and radioisotopes. However, this method inevitably exposes patients and physicians to radiation, and the special facilities required limit its accessibility. Here, we demonstrate a non-ionizing, cost-effective, handheld photoacoustic finder (PAF) fully integrated with a solid-state dye laser and transparent ultrasound transducer (TUT). The solid-state dye laser handpiece is coaxially aligned with the spherically focused TUT. The integrated finder readily detected photo acoustic signals from a tube filled with methylene blue (MB) beneath a 22 mm thick layer of chicken tissue. In live animals, we also photoacoustically detected both SLNs injected with MB and subcutaneously injected melanomas. We believe that our radiation-free and inexpensive PAF can play a vital role in SLN assessment.
- URI
- https://oasis.postech.ac.kr/handle/2014.oak/107670
- DOI
- 10.1016/j.pacs.2021.100290
- ISSN
- 2213-5979
- Article Type
- Article
- Citation
- PHOTOACOUSTICS, vol. 23, page. 100290, 2021-09
- Files in This Item:
- There are no files associated with this item.
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.