The CEP5 Peptide Promotes Abiotic Stress Tolerance, As Revealed by Quantitative Proteomics, and Attenuates the AUX/IAA Equilibrium in Arabidopsis
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SCOPUS
- Title
- The CEP5 Peptide Promotes Abiotic Stress Tolerance, As Revealed by Quantitative Proteomics, and Attenuates the AUX/IAA Equilibrium in Arabidopsis
- Authors
- Smith, Stephanie; Zhu, Shanshuo; Joos, Lisa; Roberts, Ianto; Nikonorova, Natalia; Vu, Lam Dai; Stes, Elisabeth; Cho, Hyunwoo; Larrieu, Antoine; Xuan, Wei; Goodall, Benjamin; van de Cotte, Brigitte; Waite, Jessic Marie; Rigal, Adeline; Harborough, Sigurd Ramans; Persiau, Geert; Vanneste, Steffen; Kirschner, Gwendolyn K.; Vandermarliere, Elien; Martens, Lennart; Stahl, Yvonne; Audenaert, Dominique; Friml, Jiri; Felix, Georg; Simon, Ruediger; Bennett, Malcolm J.; Bishopp, Anthony; De Jaeger, Geert; Ljung, Karin; Kepinski, Stefan; Robert, Stephanie; Nemhauser, Jennifer; Hwang, Ildoo; Gevaert, Kris; Beeckman, Tom; De Smet, Ive
- Date Issued
- 2020-08
- Publisher
- AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC
- Abstract
- Peptides derived from non-functional precursors play important roles in various developmental processes, but also in (a)biotic stress signaling. Our (phospho)proteome-wide analyses of C-TERMINALLY ENCODED PEPTIDE 5 (CEP5)-mediated changes revealed an impact on abiotic stress-related processes. Drought has a dramatic impact on plant growth, development and reproduction, and the plant hormone auxin plays a role in drought responses. Our genetic, physiological, biochemical, and pharmacological results demonstrated that CEP5-mediated signaling is relevant for osmotic and drought stress tolerance in Arabidopsis, and that CEP5 specifically counteracts auxin effects. Specifically, we found that CEP5 signaling stabi-lizes AUX/IAA transcriptional repressors, suggesting the existence of a novel peptide-dependent control mechanism that tunes auxin signaling. These observations align with the recently described role of AUX/IAAs in stress tolerance and provide a novel role for CEP5 in osmotic and drought stress tolerance.
- URI
- https://oasis.postech.ac.kr/handle/2014.oak/106912
- DOI
- 10.1074/mcp.RA119.001826
- ISSN
- 1535-9476
- Article Type
- Article
- Citation
- MOLECULAR & CELLULAR PROTEOMICS, vol. 19, no. 8, page. 1248 - 1262, 2020-08
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