DC Field | Value | Language |
---|---|---|
dc.contributor.author | Shim, S | - |
dc.contributor.author | Bae, N | - |
dc.contributor.author | Park, SY | - |
dc.contributor.author | Kim, WS | - |
dc.contributor.author | Han, JK | - |
dc.date.accessioned | 2016-04-01T02:08:13Z | - |
dc.date.available | 2016-04-01T02:08:13Z | - |
dc.date.created | 2009-03-18 | - |
dc.date.issued | 2005-06-30 | - |
dc.identifier.issn | 1016-8478 | - |
dc.identifier.other | 2005-OAK-0000005245 | - |
dc.identifier.uri | https://oasis.postech.ac.kr/handle/2014.oak/24500 | - |
dc.description.abstract | The Xenopus FGF-8a and FGF-8b isoforms have been reported to be neural crest and neuronal inducers, respectively. However, cloning of Xenopus FGF-8b (XFGF-8b) has not been reported previously and the two isoforms do not seem to have been clearly distinguished in Xenopus experiments. Here, we describe the cloning and expression of XFGF-8b and compare the effects of the two isoforms. XFGF-8b has an 11 amino acid insert in its N-terminal region compared with XFGF-8a. Both isoforms are expressed in the anterior neural regions of the early embryo, and in the apical ectodermal ridge of limb buds and tips of growing digits in the larval stages. However, XFGF-8b is more abundant than XFGF-8a throughout early development. The two isoforms are also regulated in similar fashion by retinoic acid in early development. However, although both XFGF-8a and XFGF-8b induce ectopic neurogenesis, only XFGF-8a appears to be involved in neural crest induction. | - |
dc.description.statementofresponsibility | X | - |
dc.language | English | - |
dc.publisher | SPRINGER SINGAPORE PTE LTD | - |
dc.relation.isPartOf | MOLECULES AND CELLS | - |
dc.subject | embryogenesis | - |
dc.subject | FGF-8 | - |
dc.subject | in situ hybridization | - |
dc.subject | neural crest | - |
dc.subject | neurogenesis | - |
dc.subject | retinoic acid | - |
dc.subject | Xenopus laevis | - |
dc.subject | INDUCED GROWTH-FACTOR | - |
dc.subject | NEURONAL DIFFERENTIATION | - |
dc.subject | BIOLOGICAL-ACTIVITY | - |
dc.subject | RECEPTOR-BINDING | - |
dc.subject | FGF8 | - |
dc.subject | EXPRESSION | - |
dc.subject | INDUCTION | - |
dc.subject | CELLS | - |
dc.subject | LIMB | - |
dc.subject | MESODERM | - |
dc.title | Isolation of Xenopus FGF-8b and comparison with FGF-8a | - |
dc.type | Article | - |
dc.contributor.college | 생명과학과 | - |
dc.author.google | Shim, S | - |
dc.author.google | Bae, N | - |
dc.author.google | Park, SY | - |
dc.author.google | Kim, WS | - |
dc.author.google | Han, JK | - |
dc.relation.volume | 19 | - |
dc.relation.issue | 3 | - |
dc.relation.startpage | 310 | - |
dc.relation.lastpage | 317 | - |
dc.contributor.id | 10138853 | - |
dc.relation.journal | MOLECULES AND CELLS | - |
dc.relation.index | SCI급, SCOPUS 등재논문 | - |
dc.relation.sci | SCI | - |
dc.collections.name | Journal Papers | - |
dc.type.rims | ART | - |
dc.identifier.bibliographicCitation | MOLECULES AND CELLS, v.19, no.3, pp.310 - 317 | - |
dc.identifier.wosid | 000230342100002 | - |
dc.date.tcdate | 2019-02-01 | - |
dc.citation.endPage | 317 | - |
dc.citation.number | 3 | - |
dc.citation.startPage | 310 | - |
dc.citation.title | MOLECULES AND CELLS | - |
dc.citation.volume | 19 | - |
dc.contributor.affiliatedAuthor | Han, JK | - |
dc.description.journalClass | 1 | - |
dc.description.journalClass | 1 | - |
dc.description.wostc | 11 | - |
dc.type.docType | Article | - |
dc.subject.keywordPlus | INDUCED GROWTH-FACTOR | - |
dc.subject.keywordPlus | BIOLOGICAL-ACTIVITY | - |
dc.subject.keywordPlus | FGF8 | - |
dc.subject.keywordPlus | EXPRESSION | - |
dc.subject.keywordPlus | INDUCTION | - |
dc.subject.keywordPlus | MESODERM | - |
dc.subject.keywordPlus | MIDBRAIN | - |
dc.subject.keywordPlus | ISOFORMS | - |
dc.subject.keywordPlus | REGIONS | - |
dc.subject.keywordPlus | FAMILY | - |
dc.subject.keywordAuthor | embryogenesis | - |
dc.subject.keywordAuthor | FGF-8 | - |
dc.subject.keywordAuthor | in situ hybridization | - |
dc.subject.keywordAuthor | neural crest | - |
dc.subject.keywordAuthor | neurogenesis | - |
dc.subject.keywordAuthor | retinoic acid | - |
dc.subject.keywordAuthor | Xenopus laevis | - |
dc.relation.journalWebOfScienceCategory | Biochemistry & Molecular Biology | - |
dc.relation.journalWebOfScienceCategory | Cell Biology | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.description.journalRegisteredClass | kci | - |
dc.relation.journalResearchArea | Biochemistry & Molecular Biology | - |
dc.relation.journalResearchArea | Cell Biology | - |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.
library@postech.ac.kr Tel: 054-279-2548
Copyrights © by 2017 Pohang University of Science ad Technology All right reserved.