DC Field | Value | Language |
---|---|---|
dc.contributor.author | Kim, DY | - |
dc.contributor.author | Bovet, L | - |
dc.contributor.author | Maeshima, M | - |
dc.contributor.author | Martinoia, E | - |
dc.contributor.author | Lee, Y | - |
dc.date.accessioned | 2016-04-01T01:40:29Z | - |
dc.date.available | 2016-04-01T01:40:29Z | - |
dc.date.created | 2009-08-25 | - |
dc.date.issued | 2007-04 | - |
dc.identifier.issn | 0960-7412 | - |
dc.identifier.other | 2007-OAK-0000006756 | - |
dc.identifier.uri | https://oasis.postech.ac.kr/handle/2014.oak/23454 | - |
dc.description.abstract | Cadmium (Cd) and lead (Pb) are widespread pollutants that are toxic to plant growth. The expression of AtPDR8 was upregulated in cadmium- or lead-treated Arabidopsis thaliana. To test whether AtPDR8 is involved in heavy metal resistance, we examined transgenic Arabidopsis that over-expressed AtPDR8 and RNAi plants that exhibited a severely reduced AtPDR8 transcript level, as well as T-DNA insertion mutants of this ABC transporter. AtPDR8-over-expressing plants were more resistant to Cd2+ or Pb2+ than the wild-type and had lower Cd contents. In contrast, AtPDR8 RNAi transgenic plants and T-DNA insertion lines were more sensitive to Cd2+ or Pb2+ compared to wild-type plants and had higher Cd contents. The GFP-AtPDR8 protein was targeted to the plasma membrane, and GUS activity was present in most cells but strongest in the root hair and epidermal cells. Cd extrusion was higher in the AtPDR8-over-expressing plants in a flux assay using isolated protoplasts and radioactive Cd-109, and was lower in the RNAi transgenic plants than in the wild-type. Together, these data strongly support a role for AtPDR8 as an efflux pump of Cd2+ or Cd conjugates at the plasma membrane of Arabidopsis cells. As AtPDR8 has been suggested to be involved in the pathogen response and in the transport of chemicals that mediate pathogen resistance, this ABC protein is likely to transport a very broad range of substrates. | - |
dc.description.statementofresponsibility | X | - |
dc.language | English | - |
dc.publisher | BLACKWELL PUBLISHING | - |
dc.relation.isPartOf | PLANT JOURNAL | - |
dc.subject | ABC transporter | - |
dc.subject | heavy metal resistance | - |
dc.subject | cadmium efflux | - |
dc.subject | lead | - |
dc.subject | Arabidopsis mutant | - |
dc.subject | AtPDR8 | - |
dc.subject | BINDING CASSETTE TRANSPORTER | - |
dc.subject | ARABIDOPSIS-THALIANA | - |
dc.subject | ESCHERICHIA-COLI | - |
dc.subject | SACCHAROMYCES-CEREVISIAE | - |
dc.subject | VACUOLAR MEMBRANE | - |
dc.subject | CHLORIDE CHANNEL | - |
dc.subject | RICE ROOTS | - |
dc.subject | PROTEIN | - |
dc.subject | GENE | - |
dc.subject | ATPASE | - |
dc.title | The ABC transporter AtPDR8 is a cadmium extrusion pump conferring heavy metal resistance | - |
dc.type | Article | - |
dc.contributor.college | 생명과학과 | - |
dc.identifier.doi | 10.1111/j.1365-313X.2007.03044.x | - |
dc.author.google | Kim, DY | - |
dc.author.google | Bovet, L | - |
dc.author.google | Maeshima, M | - |
dc.author.google | Martinoia, E | - |
dc.author.google | Lee, Y | - |
dc.relation.volume | 50 | - |
dc.relation.issue | 2 | - |
dc.relation.startpage | 207 | - |
dc.relation.lastpage | 218 | - |
dc.contributor.id | 10175128 | - |
dc.relation.journal | PLANT JOURNAL | - |
dc.relation.index | SCI급, SCOPUS 등재논문 | - |
dc.relation.sci | SCI | - |
dc.collections.name | Journal Papers | - |
dc.type.rims | ART | - |
dc.identifier.bibliographicCitation | PLANT JOURNAL, v.50, no.2, pp.207 - 218 | - |
dc.identifier.wosid | 000245697900003 | - |
dc.date.tcdate | 2018-12-01 | - |
dc.citation.endPage | 218 | - |
dc.citation.number | 2 | - |
dc.citation.startPage | 207 | - |
dc.citation.title | PLANT JOURNAL | - |
dc.citation.volume | 50 | - |
dc.contributor.affiliatedAuthor | Lee, Y | - |
dc.identifier.scopusid | 2-s2.0-34247270870 | - |
dc.description.journalClass | 1 | - |
dc.description.journalClass | 1 | - |
dc.description.wostc | 245 | - |
dc.type.docType | Article | - |
dc.subject.keywordPlus | BINDING CASSETTE TRANSPORTER | - |
dc.subject.keywordPlus | ARABIDOPSIS-THALIANA | - |
dc.subject.keywordPlus | ESCHERICHIA-COLI | - |
dc.subject.keywordPlus | SACCHAROMYCES-CEREVISIAE | - |
dc.subject.keywordPlus | VACUOLAR MEMBRANE | - |
dc.subject.keywordPlus | CHLORIDE CHANNEL | - |
dc.subject.keywordPlus | RICE ROOTS | - |
dc.subject.keywordPlus | PROTEIN | - |
dc.subject.keywordPlus | GENE | - |
dc.subject.keywordPlus | ATPASE | - |
dc.subject.keywordAuthor | ABC transporter | - |
dc.subject.keywordAuthor | heavy metal resistance | - |
dc.subject.keywordAuthor | cadmium efflux | - |
dc.subject.keywordAuthor | lead | - |
dc.subject.keywordAuthor | Arabidopsis mutant | - |
dc.subject.keywordAuthor | AtPDR8 | - |
dc.relation.journalWebOfScienceCategory | Plant Sciences | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Plant Sciences | - |
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