DC Field | Value | Language |
---|---|---|
dc.contributor.author | HAN, JK | - |
dc.date.accessioned | 2016-03-31T14:33:40Z | - |
dc.date.available | 2016-03-31T14:33:40Z | - |
dc.date.created | 2009-03-18 | - |
dc.date.issued | 1995-01-17 | - |
dc.identifier.issn | 0006-291X | - |
dc.identifier.other | 1995-OAK-0000009030 | - |
dc.identifier.uri | https://oasis.postech.ac.kr/handle/2014.oak/21862 | - |
dc.description.abstract | Evidence suggests that a transient increase in intracellular calcium ([Ca2+](i)) is an important modulator during the cell division cycle in early embryos. We have recently shown that inhibition of Ins(1,4,5)P-3-induced Ca2+ release in the cleaving Xenopus embryos greatly lengthens the cell cycle duration. In this report, we have directly measured the changes of Ins(1,4,5)P-3 content during the first two cleavage cycles in the Xenopus embryos. HPLC profiles of cell extracts from dividing embryos show oscillations of inositol polyphosphates throughout the cleavage cycle with a transient production of Ins(1,4,5)P-3 by the time of cleavage furrow completion. In addition, cyclic changes in inositol phospholipids, phosphatidylinositol 4,5-bisphosphate (PIP2) and phosphatidylinositol 4-phosphate (PIP) were detected during the cleavage cycle. These data strongly suggest the involvement of PIP2 turnover and periodic increase in Ins(1,4,5)P-3 triggers [Ca2+](i) transients during the early embryonic cell cycle in the Xenopus. (C) 1995 Academic Press, Inc. | - |
dc.description.statementofresponsibility | X | - |
dc.language | English | - |
dc.publisher | ACADEMIC PRESS INC JNL-COMP SUBSCRIPT | - |
dc.relation.isPartOf | BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS | - |
dc.subject | INTRACELLULAR FREE CALCIUM | - |
dc.subject | CELL-CYCLE | - |
dc.subject | LIPID HYDROLYSIS | - |
dc.subject | CA2+ WAVE | - |
dc.subject | PHOSPHATES | - |
dc.subject | MITOSIS | - |
dc.subject | EGG | - |
dc.title | OSCILLATION OF INOSITOL POLYPHOSPHATES IN THE EMBRYONIC CLEAVAGE CYCLE OF THE XENOPUS-LAEVIS | - |
dc.type | Article | - |
dc.contributor.college | 생명과학과 | - |
dc.identifier.doi | 10.1006/bbrc.1995.1109 | - |
dc.author.google | HAN, JK | - |
dc.relation.volume | 206 | - |
dc.relation.issue | 2 | - |
dc.relation.startpage | 775 | - |
dc.relation.lastpage | 780 | - |
dc.contributor.id | 10138853 | - |
dc.relation.journal | BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS | - |
dc.relation.index | SCI급, SCOPUS 등재논문 | - |
dc.relation.sci | SCI | - |
dc.collections.name | Journal Papers | - |
dc.type.rims | ART | - |
dc.identifier.bibliographicCitation | BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, v.206, no.2, pp.775 - 780 | - |
dc.identifier.wosid | A1995QC11500048 | - |
dc.date.tcdate | 2019-01-01 | - |
dc.citation.endPage | 780 | - |
dc.citation.number | 2 | - |
dc.citation.startPage | 775 | - |
dc.citation.title | BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS | - |
dc.citation.volume | 206 | - |
dc.contributor.affiliatedAuthor | HAN, JK | - |
dc.identifier.scopusid | 2-s2.0-0028928645 | - |
dc.description.journalClass | 1 | - |
dc.description.journalClass | 1 | - |
dc.description.wostc | 6 | - |
dc.type.docType | Article | - |
dc.subject.keywordPlus | INTRACELLULAR FREE CALCIUM | - |
dc.subject.keywordPlus | CELL-CYCLE | - |
dc.subject.keywordPlus | LIPID HYDROLYSIS | - |
dc.subject.keywordPlus | CA2+ WAVE | - |
dc.subject.keywordPlus | PHOSPHATES | - |
dc.subject.keywordPlus | MITOSIS | - |
dc.subject.keywordPlus | EGG | - |
dc.relation.journalWebOfScienceCategory | Biochemistry & Molecular Biology | - |
dc.relation.journalWebOfScienceCategory | Biophysics | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Biochemistry & Molecular Biology | - |
dc.relation.journalResearchArea | Biophysics | - |
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