DC Field | Value | Language |
---|---|---|
dc.contributor.author | Choi, SC | - |
dc.contributor.author | Kim, J | - |
dc.contributor.author | Han, JK | - |
dc.date.accessioned | 2016-03-31T13:32:54Z | - |
dc.date.available | 2016-03-31T13:32:54Z | - |
dc.date.created | 2009-03-18 | - |
dc.date.issued | 2000-03-01 | - |
dc.identifier.issn | 0925-4773 | - |
dc.identifier.other | 2000-OAK-0000001227 | - |
dc.identifier.uri | https://oasis.postech.ac.kr/handle/2014.oak/20071 | - |
dc.description.abstract | The par genes (partitioning defective) are required to establish polarity in the Caenorhabditis elegans embryo. We have identified the Xenopus homologue of C. elegans PAR-6 (XPAR-6). XPAR-6 is a protein of 377 amino acids with one PDZ domain which is involved in mediating protein-protein interactions. It shares 59% and 58% amino acid identity with the mouse and Drosophila PAR-6, respectively, and 54% overall identity with C. elegans PAR-6. Xpar-6 is expressed both maternally and zygotically. Xpar-6 is first detected in the animal half of the egg, and this pattern of expression persists into the cleavage and blastula stages. At the gastrula stage, the message is detected in animal pole area and in a broad domain of ventral region, but is excluded from dorsal region. With the onset of neurulation, the localized expression of Xpar-6 becomes more obvious, leading to it being enriched in the dorsolateral region along the lateral edges of neural plate and anterior presumptive head region surrounding the anterior border of neural plate. At late tailbud stage, Xpar-6 transcripts show localized expression throughout the head, labeling the branchial arches, eyes, otic vesicles and brain, while more posteriorly Xpar-6 labels the somites, pronephros, tail tip and proctodeum. Therefore, this analysis suggests that Xpar-6 has a regionalized pattern of expression during Xenopus early embryogenesis. (C) 2000 Elsevier Science Ireland Ltd. All rights reserved. | - |
dc.description.statementofresponsibility | X | - |
dc.language | English | - |
dc.publisher | ELSEVIER SCIENCE BV | - |
dc.relation.isPartOf | MECHANISMS OF DEVELOPMENT | - |
dc.subject | Xenopus laevis | - |
dc.subject | par | - |
dc.subject | PAR-6 | - |
dc.subject | PDZ domain | - |
dc.subject | embryogenesis | - |
dc.subject | somite | - |
dc.subject | branchial arch | - |
dc.subject | otic vesicle | - |
dc.subject | pronephros | - |
dc.subject | MOLECULES | - |
dc.title | Identification and developmental expression of par-6 gene in Xenopus laevis | - |
dc.type | Article | - |
dc.contributor.college | 생명과학과 | - |
dc.identifier.doi | 10.1016/S0925-4773(99)00281-6 | - |
dc.author.google | Choi, SC | - |
dc.author.google | Kim, J | - |
dc.author.google | Han, JK | - |
dc.relation.volume | 91 | - |
dc.relation.issue | 1-2 | - |
dc.relation.startpage | 347 | - |
dc.relation.lastpage | 350 | - |
dc.contributor.id | 10138853 | - |
dc.relation.journal | MECHANISMS OF DEVELOPMENT | - |
dc.relation.index | SCI급, SCOPUS 등재논문 | - |
dc.relation.sci | SCI | - |
dc.collections.name | Journal Papers | - |
dc.type.rims | ART | - |
dc.identifier.bibliographicCitation | MECHANISMS OF DEVELOPMENT, v.91, no.1-2, pp.347 - 350 | - |
dc.identifier.wosid | 000086146500037 | - |
dc.date.tcdate | 2019-01-01 | - |
dc.citation.endPage | 350 | - |
dc.citation.number | 1-2 | - |
dc.citation.startPage | 347 | - |
dc.citation.title | MECHANISMS OF DEVELOPMENT | - |
dc.citation.volume | 91 | - |
dc.contributor.affiliatedAuthor | Han, JK | - |
dc.identifier.scopusid | 2-s2.0-0034003326 | - |
dc.description.journalClass | 1 | - |
dc.description.journalClass | 1 | - |
dc.description.wostc | 13 | - |
dc.type.docType | Article | - |
dc.subject.keywordAuthor | Xenopus laevis | - |
dc.subject.keywordAuthor | par | - |
dc.subject.keywordAuthor | PAR-6 | - |
dc.subject.keywordAuthor | PDZ domain | - |
dc.subject.keywordAuthor | embryogenesis | - |
dc.subject.keywordAuthor | somite | - |
dc.subject.keywordAuthor | branchial arch | - |
dc.subject.keywordAuthor | otic vesicle | - |
dc.subject.keywordAuthor | pronephros | - |
dc.relation.journalWebOfScienceCategory | Developmental Biology | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Developmental Biology | - |
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