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| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Kim, MJ | - |
| dc.contributor.author | Kim, E | - |
| dc.contributor.author | Ryu, SH | - |
| dc.contributor.author | Suh, PG | - |
| dc.date.accessioned | 2016-03-31T13:26:31Z | - |
| dc.date.available | 2016-03-31T13:26:31Z | - |
| dc.date.created | 2009-08-12 | - |
| dc.date.issued | 2000-09-30 | - |
| dc.identifier.issn | 1226-3613 | - |
| dc.identifier.other | 2000-OAK-0000001575 | - |
| dc.identifier.uri | https://oasis.postech.ac.kr/handle/2014.oak/19833 | - |
| dc.description.abstract | Phospholipase C (PLC)(1) hydrolyzes phosphatidylinositol 4,5-bisphosphate to generate the second messengers, inositol 1,4,5-trisphosphate (IP3) and diacylglycerol (DAG). IP3 induces a transient increase in intracellular free Ca2+, while DAG directly activates protein kinase C. Upon stimulation of cells with growth factors, PLC-gamma 1 is activated upon their association with and phosphorylation by receptor and non-receptor tyrosine kinases. In this review, we will focus on the activation mechanism and regulatory function of PLC-gamma 1. | - |
| dc.description.statementofresponsibility | X | - |
| dc.language | English | - |
| dc.publisher | KOREAN SOC MED BIOCHEMISTRY MOLECULAR | - |
| dc.relation.isPartOf | EXPERIMENTAL AND MOLECULAR MEDICINE | - |
| dc.title | The mechanism of phospholipase C-gamma 1 regulation | - |
| dc.type | Article | - |
| dc.contributor.college | 생명과학과 | - |
| dc.identifier.doi | 10.1038/emm.2000.18 | - |
| dc.author.google | Kim, MJ | - |
| dc.author.google | Kim, E | - |
| dc.author.google | Ryu, SH | - |
| dc.author.google | Suh, PG | - |
| dc.relation.volume | 32 | - |
| dc.relation.issue | 3 | - |
| dc.relation.startpage | 101 | - |
| dc.relation.lastpage | 109 | - |
| dc.contributor.id | 10069853 | - |
| dc.relation.journal | EXPERIMENTAL AND MOLECULAR MEDICINE | - |
| dc.relation.index | SCI급, SCOPUS 등재논문 | - |
| dc.relation.sci | SCI | - |
| dc.collections.name | Journal Papers | - |
| dc.type.rims | ART | - |
| dc.identifier.bibliographicCitation | EXPERIMENTAL AND MOLECULAR MEDICINE, v.32, no.3, pp.101 - 109 | - |
| dc.identifier.wosid | 000089869500001 | - |
| dc.date.tcdate | 2019-01-01 | - |
| dc.citation.endPage | 109 | - |
| dc.citation.number | 3 | - |
| dc.citation.startPage | 101 | - |
| dc.citation.title | EXPERIMENTAL AND MOLECULAR MEDICINE | - |
| dc.citation.volume | 32 | - |
| dc.contributor.affiliatedAuthor | Ryu, SH | - |
| dc.contributor.affiliatedAuthor | Suh, PG | - |
| dc.identifier.scopusid | 2-s2.0-0034734605 | - |
| dc.description.journalClass | 1 | - |
| dc.description.journalClass | 1 | - |
| dc.description.wostc | 55 | - |
| dc.type.docType | Article | - |
| dc.subject.keywordPlus | GROWTH-FACTOR RECEPTOR | - |
| dc.subject.keywordPlus | TERMINAL SH2 DOMAIN | - |
| dc.subject.keywordPlus | PROTEIN-KINASE-C | - |
| dc.subject.keywordPlus | SIGNAL-TRANSDUCTION | - |
| dc.subject.keywordPlus | T-CELL | - |
| dc.subject.keywordPlus | ARACHIDONIC-ACID | - |
| dc.subject.keywordPlus | TYROSINE KINASES | - |
| dc.subject.keywordPlus | ELEVATED CONTENT | - |
| dc.subject.keywordPlus | ALPHA-SUBUNITS | - |
| dc.subject.keywordPlus | DNA-SYNTHESIS | - |
| dc.relation.journalWebOfScienceCategory | Biochemistry & Molecular Biology | - |
| dc.relation.journalWebOfScienceCategory | Medicine, Research & Experimental | - |
| dc.description.journalRegisteredClass | scie | - |
| dc.description.journalRegisteredClass | scopus | - |
| dc.relation.journalResearchArea | Biochemistry & Molecular Biology | - |
| dc.relation.journalResearchArea | Research & Experimental Medicine | - |
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Related Researcher
- 류성호RYU, SUNG HO
- Dept of Life Sciences