DC Field | Value | Language |
---|---|---|
dc.contributor.author | Yoo, JS | - |
dc.contributor.author | Kim, HB | - |
dc.contributor.author | Won, N | - |
dc.contributor.author | Bang, J | - |
dc.contributor.author | Kim, S | - |
dc.contributor.author | Ahn, S | - |
dc.contributor.author | Lee, BC | - |
dc.contributor.author | Soh, KS | - |
dc.date.accessioned | 2016-03-31T09:38:00Z | - |
dc.date.available | 2016-03-31T09:38:00Z | - |
dc.date.created | 2011-06-07 | - |
dc.date.issued | 2011-06 | - |
dc.identifier.issn | 1536-1632 | - |
dc.identifier.other | 2011-OAK-0000023647 | - |
dc.identifier.uri | https://oasis.postech.ac.kr/handle/2014.oak/17422 | - |
dc.description.abstract | Researchers have been studying the mechanisms by which metastasis can be prevented via blocking the hematogenous and the lymphatic routes for a long time now. However, metastasis is still the single most challenging obstacle for successful cancer management. In a new twist that may require some retooling of this established approach, we investigated the hypothesis that tumor metastases can occur via an independent fluid-conducting system called the primo-vascular system. The dissemination and growth of near-infrared quantum dot (NIR QD)-electroporated cancer cells in metastatic sites were investigated using in vivo multispectral imaging techniques. Our results show that the NIR QD-labeled cancer cells were able to migrate through not only the blood vascular and lymphatic systems but also the primo-vascular system extending from around the tumor to inside the abdominal cavity. Furthermore, the NIR QD-labeled cancer cells, which had been seeded intraperitoneally, specifically infiltrated the primo-vascular system in the omentum and in the gonadal fat. These findings strongly suggest that the primo-vascular system may be an additional metastasis route, complementing the lymphatic and hematogenous routes, which facilitate the dissemination and colonization of cancer cells at secondary sites. | - |
dc.description.statementofresponsibility | X | - |
dc.language | English | - |
dc.publisher | SPRINGER | - |
dc.relation.isPartOf | MOLECULAR IMAGING AND BIOLOGY | - |
dc.subject | Cancer metastasis | - |
dc.subject | Primo-vascular system | - |
dc.subject | Multispectral imaging | - |
dc.subject | Electroporation | - |
dc.subject | Near-infrared quantum dots | - |
dc.subject | Vasculogenic mimicry | - |
dc.subject | QUANTUM DOTS | - |
dc.subject | VASCULOGENIC MIMICRY | - |
dc.subject | DISSEMINATION | - |
dc.subject | MELANOMA | - |
dc.subject | TRACKING | - |
dc.subject | MODEL | - |
dc.subject | MICROSCOPY | - |
dc.subject | MICE | - |
dc.title | Evidence for an Additional Metastatic Route: In Vivo Imaging of Cancer Cells in the Primo-Vascular System Around Tumors and Organs | - |
dc.type | Article | - |
dc.contributor.college | 화학과 | - |
dc.identifier.doi | 10.1007/S11307-010-0366-1 | - |
dc.author.google | Yoo, JS | - |
dc.author.google | Kim, HB | - |
dc.author.google | Won, N | - |
dc.author.google | Bang, J | - |
dc.author.google | Kim, S | - |
dc.author.google | Ahn, S | - |
dc.author.google | Lee, BC | - |
dc.author.google | Soh, KS | - |
dc.relation.volume | 13 | - |
dc.relation.issue | 3 | - |
dc.relation.startpage | 471 | - |
dc.relation.lastpage | 480 | - |
dc.contributor.id | 10149571 | - |
dc.relation.journal | MOLECULAR IMAGING AND BIOLOGY | - |
dc.relation.index | SCI급, SCOPUS 등재논문 | - |
dc.relation.sci | SCIE | - |
dc.collections.name | Journal Papers | - |
dc.type.rims | ART | - |
dc.identifier.bibliographicCitation | MOLECULAR IMAGING AND BIOLOGY, v.13, no.3, pp.471 - 480 | - |
dc.identifier.wosid | 000290277300009 | - |
dc.date.tcdate | 2019-01-01 | - |
dc.citation.endPage | 480 | - |
dc.citation.number | 3 | - |
dc.citation.startPage | 471 | - |
dc.citation.title | MOLECULAR IMAGING AND BIOLOGY | - |
dc.citation.volume | 13 | - |
dc.contributor.affiliatedAuthor | Kim, S | - |
dc.identifier.scopusid | 2-s2.0-79956220664 | - |
dc.description.journalClass | 1 | - |
dc.description.journalClass | 1 | - |
dc.description.wostc | 45 | - |
dc.description.scptc | 39 | * |
dc.date.scptcdate | 2018-05-121 | * |
dc.type.docType | Article | - |
dc.subject.keywordPlus | QUANTUM DOTS | - |
dc.subject.keywordPlus | VASCULOGENIC MIMICRY | - |
dc.subject.keywordPlus | DISSEMINATION | - |
dc.subject.keywordPlus | MELANOMA | - |
dc.subject.keywordPlus | TRACKING | - |
dc.subject.keywordPlus | MODEL | - |
dc.subject.keywordPlus | MICROSCOPY | - |
dc.subject.keywordPlus | MICE | - |
dc.subject.keywordAuthor | Cancer metastasis | - |
dc.subject.keywordAuthor | Primo-vascular system | - |
dc.subject.keywordAuthor | Multispectral imaging | - |
dc.subject.keywordAuthor | Electroporation | - |
dc.subject.keywordAuthor | Near-infrared quantum dots | - |
dc.subject.keywordAuthor | Vasculogenic mimicry | - |
dc.relation.journalWebOfScienceCategory | Radiology, Nuclear Medicine & Medical Imaging | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Radiology, Nuclear Medicine & Medical Imaging | - |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.
library@postech.ac.kr Tel: 054-279-2548
Copyrights © by 2017 Pohang University of Science ad Technology All right reserved.