DC Field | Value | Language |
---|---|---|
dc.contributor.author | Hong-Ryul Jung | - |
dc.contributor.author | Jong-Cheol Choi | - |
dc.contributor.author | Wonhwa Cho | - |
dc.contributor.author | Doh, J | - |
dc.date.accessioned | 2016-03-31T08:50:27Z | - |
dc.date.available | 2016-03-31T08:50:27Z | - |
dc.date.created | 2015-02-05 | - |
dc.date.issued | 2013-01 | - |
dc.identifier.issn | 1939-5116 | - |
dc.identifier.other | 2013-OAK-0000026314 | - |
dc.identifier.uri | https://oasis.postech.ac.kr/handle/2014.oak/16156 | - |
dc.description.abstract | Immunological synapse (IS) is a complex supramolecular structure formed at the interface between T cells and antigen presenting cells (APCs) during T cell antigen recognition. Microfabricated platforms have made great contributions to our understanding of the assembly dynamics and functional roles of the T cell synapses over the last decade. Here, we review three different types of microfabricated platforms developed to modulate andmonitor the T cell synapse assembly. Firstly, multi-protein micropatterned surfaces presenting key ligands for T cell activation that can modulate the spatial distribution of receptors/signaling molecules in T cell synapses are described. Secondly, micropatterned supported bilayers that can modulate the dynamics of T cell receptor (TCR) microclusters are introduced. Lastly, T-APC pair arrays that allow for improved fluorescence live cell imaging are discussed. (C) 2012 Wiley Periodicals, Inc. | - |
dc.description.statementofresponsibility | X | - |
dc.language | English | - |
dc.publisher | Wiley Periodicals, Inc. | - |
dc.relation.isPartOf | Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology | - |
dc.subject | SUPRAMOLECULAR ACTIVATION CLUSTER | - |
dc.subject | KINASE-C-THETA | - |
dc.subject | IMMUNOLOGICAL SYNAPSE | - |
dc.subject | ANTIGEN RECEPTOR | - |
dc.subject | SIGNALING MOLECULES | - |
dc.subject | LIGAND RECOGNITION | - |
dc.subject | MICROCLUSTERS | - |
dc.subject | SURFACES | - |
dc.subject | BILAYERS | - |
dc.subject | LYMPHOCYTES | - |
dc.title | Microfabricated platforms to modulate and monitor T cell synapse assembly | - |
dc.type | Article | - |
dc.contributor.college | 기계공학과 | - |
dc.identifier.doi | 10.1002/WNAN.1182 | - |
dc.author.google | Jung, HR | - |
dc.author.google | Choi, JC | - |
dc.author.google | Cho, W | - |
dc.author.google | Doh, J | - |
dc.relation.volume | 5 | - |
dc.relation.issue | 1 | - |
dc.relation.startpage | 67 | - |
dc.relation.lastpage | 74 | - |
dc.contributor.id | 10189091 | - |
dc.relation.journal | Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology | - |
dc.relation.index | SCI급, SCOPUS 등재논문 | - |
dc.relation.sci | SCIE | - |
dc.collections.name | Journal Papers | - |
dc.type.rims | ART | - |
dc.identifier.bibliographicCitation | Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology, v.5, no.1, pp.67 - 74 | - |
dc.identifier.wosid | 000314987200005 | - |
dc.date.tcdate | 2019-01-01 | - |
dc.citation.endPage | 74 | - |
dc.citation.number | 1 | - |
dc.citation.startPage | 67 | - |
dc.citation.title | Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology | - |
dc.citation.volume | 5 | - |
dc.contributor.affiliatedAuthor | Doh, J | - |
dc.identifier.scopusid | 2-s2.0-84871668163 | - |
dc.description.journalClass | 1 | - |
dc.description.journalClass | 1 | - |
dc.description.wostc | 5 | - |
dc.description.scptc | 6 | * |
dc.date.scptcdate | 2018-05-121 | * |
dc.type.docType | Review | - |
dc.subject.keywordPlus | SUPRAMOLECULAR ACTIVATION CLUSTER | - |
dc.subject.keywordPlus | KINASE-C-THETA | - |
dc.subject.keywordPlus | IMMUNOLOGICAL SYNAPSE | - |
dc.subject.keywordPlus | ANTIGEN RECEPTOR | - |
dc.subject.keywordPlus | SIGNALING MOLECULES | - |
dc.subject.keywordPlus | LIGAND RECOGNITION | - |
dc.subject.keywordPlus | MICROCLUSTERS | - |
dc.subject.keywordPlus | SURFACES | - |
dc.subject.keywordPlus | BILAYERS | - |
dc.subject.keywordPlus | LYMPHOCYTES | - |
dc.relation.journalWebOfScienceCategory | Nanoscience & Nanotechnology | - |
dc.relation.journalWebOfScienceCategory | Medicine, Research & Experimental | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Science & Technology - Other Topics | - |
dc.relation.journalResearchArea | Research & Experimental Medicine | - |
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