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Cited 64 time in webofscience Cited 66 time in scopus
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dc.contributor.authorLee, Wko
dc.contributor.authorKwon, Dko
dc.contributor.authorChung, Bko
dc.contributor.authorJung, GYko
dc.contributor.authorAu, Ako
dc.contributor.authorFolch, Ako
dc.contributor.authorJeon, Sko
dc.date.available2016-03-31T07:41:45Z-
dc.date.created2015-02-09-
dc.date.issued2014-05-
dc.identifier.citationANALYTICAL CHEMISTRY, v.86, no.13, pp.6683 - 6688-
dc.identifier.issn0003-2700-
dc.identifier.other2014-OAK-0000031510-
dc.identifier.urihttp://oasis.postech.ac.kr/handle/2014.oak/13912-
dc.description.abstractWe developed a novel 3D immunomagnetic flow assay for the rapid detection of pathogenic bacteria in a large-volume food sample. Antibody-functionalized magnetic nanoparticle clusters (AbMNCs) were magnetically immobilized on the surfaces of a 3D-printed cylindrical microchannel. The injection of a Salmonella-spiked sample solution into the microchannel produced instant binding between the AbMNCs and the Salmonella bacteria due to their efficient collisions. Nearly perfect capture of the AbMNCs and AbMNCs-Salmonella complexes was achieved under a high flow rate by stacking permanent magnets with spacers inside the cylindrical separator to maximize the magnetic force. The concentration of the bacteria in solution was determined using ATP luminescence measurements. The detection limit was better than 10 cfu/mL, and the overall assay time, including the binding, rinsing, and detection steps for a 10 mL sample took less than 3 min. To our knowledge, the 3D immunomagnetic flow assay described here provides the fastest high-sensitivity, high-capacity method for the detection of pathogenic bacteria.-
dc.description.statementofresponsibilityX-
dc.languageEnglish-
dc.publisherAMER CHEMICAL SOC-
dc.subjectMULTIPLE PATHOGENS-
dc.subjectSEPARATION-
dc.subjectMICROFLUIDICS-
dc.titleUltrarapid Detection of Pathogenic Bacteria Using a 3D Immunomagnetic Flow Assay-
dc.typeArticle-
dc.contributor.college화학공학과-
dc.identifier.doi10.1021/AC501436D-
dc.author.googleLee, W-
dc.author.googleKwon, D-
dc.author.googleChung, B-
dc.author.googleJung, GY-
dc.author.googleAu, A-
dc.author.googleFolch, A-
dc.author.googleJeon, S-
dc.relation.volume86-
dc.relation.issue13-
dc.relation.startpage6683-
dc.relation.lastpage6688-
dc.contributor.id10132035-
dc.publisher.locationUS-
dc.relation.journalANALYTICAL CHEMISTRY-
dc.relation.indexSCI급, SCOPUS 등재논문-
dc.relation.sciSCI-
dc.collections.nameJournal Papers-
dc.type.rimsART-
dc.contributor.localauthorJung, GY-
dc.contributor.localauthorJeon, S-
dc.contributor.nonIdAuthorLee, W-
dc.contributor.nonIdAuthorKwon, D-
dc.contributor.nonIdAuthorChung, B-
dc.contributor.nonIdAuthorAu, A-
dc.contributor.nonIdAuthorFolch, A-
dc.identifier.wosid000338488800071-
dc.date.tcdate2019-01-01-
dc.citation.endPage6688-
dc.citation.number13-
dc.citation.startPage6683-
dc.citation.titleANALYTICAL CHEMISTRY-
dc.citation.volume86-
dc.identifier.scopusid2-s2.0-84903712141-
dc.description.journalClass1-
dc.description.wostc45-
dc.description.scptc37*
dc.date.scptcdate2018-05-121*

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정규열JUNG, GYOO YEOL
Dept. of Chemical Enginrg
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