DC Field | Value | Language |
---|---|---|
dc.contributor.author | Choi, TY | - |
dc.contributor.author | Denton, ML | - |
dc.contributor.author | Noojin, GD | - |
dc.contributor.author | Estlack, LE | - |
dc.contributor.author | Shrestha, R | - |
dc.contributor.author | Rockwell, BA | - |
dc.contributor.author | Thomas, R | - |
dc.contributor.author | Kim, D | - |
dc.date.accessioned | 2015-06-25T02:17:31Z | - |
dc.date.available | 2015-06-25T02:17:31Z | - |
dc.date.created | 2015-02-04 | - |
dc.date.issued | 2014-09 | - |
dc.identifier.issn | 1083-3668 | - |
dc.identifier.other | 2015-OAK-0000031419 | en_US |
dc.identifier.uri | https://oasis.postech.ac.kr/handle/2014.oak/10682 | - |
dc.description.abstract | A temperature detection system using a micropipette thermocouple sensor was developed for use within mammalian cells during laser exposure with an 8.6-mu m beam at 532 nm. We have demonstrated the capability of measuring temperatures at a single-cell level in the microscale range by inserting micropipette-based thermal sensors of size ranging from 2 to 4 mu m into the membrane of a live retinal pigment epithelium (RPE) cell subjected to a laser beam. We setup the treatment groups of 532-nm laser-irradiated single RPE cell and in situ temperature recordings were made over time. Thermal profiles are given for representative cells experiencing damage resulting from exposures of 0.2 to 2 s. The measured maximum temperature rise for each cell ranges from 39 to 73 degrees C; the RPE cells showed a signature of death for all the cases reported herein. In order to check the cell viability, real-time fluorescence microscopy was used to identify the transition of pigmented RPE cells between viable and damaged states due to laser exposure. (C) 2014 Society of Photo-Optical Instrumentation Engineers (SPIE) | - |
dc.description.statementofresponsibility | open | en_US |
dc.language | English | - |
dc.publisher | SPIE-SOC PHOTO-OPTICAL INSTRUMENTATION ENGINEERS | - |
dc.relation.isPartOf | JOURNAL OF BIOMEDICAL OPTICS | - |
dc.rights | BY_NC_ND | en_US |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/2.0/kr | en_US |
dc.title | Thermal evaluation of laser exposures in an in vitro retinal model by microthermal sensing | - |
dc.type | Article | - |
dc.contributor.college | 기계공학과 | en_US |
dc.identifier.doi | 10.1117/1.JBO.19.9.097003 | - |
dc.author.google | Choi, TY | en_US |
dc.author.google | Denton, ML | en_US |
dc.author.google | Kim, D | en_US |
dc.author.google | Thomas, R | en_US |
dc.author.google | Rockwell, BA | en_US |
dc.author.google | Shrestha, R | en_US |
dc.author.google | Estlack, LE | en_US |
dc.author.google | Noojin, GD | en_US |
dc.relation.volume | 19 | en_US |
dc.relation.issue | 9 | en_US |
dc.contributor.id | 10103614 | en_US |
dc.relation.journal | JOURNAL OF BIOMEDICAL OPTICS | en_US |
dc.relation.index | SCI급, SCOPUS 등재논문 | en_US |
dc.relation.sci | SCI | en_US |
dc.collections.name | Journal Papers | en_US |
dc.type.rims | ART | - |
dc.identifier.bibliographicCitation | JOURNAL OF BIOMEDICAL OPTICS, v.19, no.9 | - |
dc.identifier.wosid | 000343874900027 | - |
dc.date.tcdate | 2018-03-23 | - |
dc.citation.number | 9 | - |
dc.citation.title | JOURNAL OF BIOMEDICAL OPTICS | - |
dc.citation.volume | 19 | - |
dc.contributor.affiliatedAuthor | Kim, D | - |
dc.identifier.scopusid | 2-s2.0-84911490155 | - |
dc.description.journalClass | 1 | - |
dc.description.journalClass | 1 | - |
dc.description.scptc | 1 | * |
dc.date.scptcdate | 2018-10-274 | * |
dc.type.docType | Article | - |
dc.subject.keywordPlus | CANCER | - |
dc.subject.keywordPlus | TEMPERATURE | - |
dc.subject.keywordPlus | THERAPY | - |
dc.subject.keywordPlus | ACID | - |
dc.subject.keywordAuthor | thermal sensing | - |
dc.subject.keywordAuthor | retinal pigment epithelium | - |
dc.subject.keywordAuthor | micropipette | - |
dc.subject.keywordAuthor | laser | - |
dc.relation.journalWebOfScienceCategory | Biochemical Research Methods | - |
dc.relation.journalWebOfScienceCategory | Optics | - |
dc.relation.journalWebOfScienceCategory | Radiology, Nuclear Medicine & Medical Imaging | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Biochemistry & Molecular Biology | - |
dc.relation.journalResearchArea | Optics | - |
dc.relation.journalResearchArea | Radiology, Nuclear Medicine & Medical Imaging | - |
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