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Cited 4 time in webofscience Cited 6 time in scopus
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dc.contributor.authorLEE, DONGHYEON-
dc.contributor.authorPARK, SEHAN-
dc.contributor.authorLEE, KEONDO-
dc.contributor.authorKIM, JANGWOO-
dc.contributor.authorPARK, GISU-
dc.contributor.authorNAM, KIHYUN-
dc.contributor.authorBAEK, SANGWON-
dc.contributor.authorCHUNG, WAN KYUN-
dc.contributor.authorLEE, JONG LAM-
dc.contributor.authorCHO, YUNJE-
dc.contributor.authorPARK, JAEHYUN-
dc.date.available2020-04-16T01:50:05Z-
dc.date.available2020-04-16T01:50:12Z-
dc.date.created2020-04-14-
dc.date.issued2020-04-
dc.identifier.issn0021-8898-
dc.identifier.urihttps://oasis.postech.ac.kr/handle/2014.oak/103443-
dc.description.abstractMicrocrystal delivery methods are pivotal in the use of serial femtosecond crystallography (SFX) to resolve the macromolecular structures of proteins. Here, the development of a novel technique and instruments for efficiently delivering microcrystals for SFX are presented. The new method, which relies on a one-dimensional fixed-target system that includes a microcrystal container, consumes an extremely low amount of sample compared with conventional two-dimensional fixed-target techniques at ambient temperature. This novel system can deliver soluble microcrystals without highly viscous carrier media and, moreover, can be used as a microcrystal growth device for SFX. Diffraction data collection utilizing this advanced technique along with a real-time visual servo scan system has been successfully demonstrated for the structure determination of proteinase K microcrystals at 1.85 Å resolution.-
dc.languageEnglish-
dc.publisherBlackwell Publishing Inc.-
dc.titleApplication of a high-throughput microcrystal delivery system to serial femtosecond crystallography-
dc.typeArticle-
dc.type.rimsART-
dc.identifier.bibliographicCitationJournal of Applied Crystallography, v.53, pp.477 - 485-
dc.identifier.wosid000524119500018-
dc.citation.endPage485-
dc.citation.startPage477-
dc.citation.titleJournal of Applied Crystallography-
dc.citation.volume53-
dc.contributor.affiliatedAuthorLEE, DONGHYEON-
dc.contributor.affiliatedAuthorLEE, KEONDO-
dc.contributor.affiliatedAuthorKIM, JANGWOO-
dc.contributor.affiliatedAuthorBAEK, SANGWON-
dc.contributor.affiliatedAuthorCHUNG, WAN KYUN-
dc.contributor.affiliatedAuthorLEE, JONG LAM-
dc.contributor.affiliatedAuthorCHO, YUNJE-
dc.contributor.affiliatedAuthorPARK, JAEHYUN-
dc.identifier.scopusid2-s2.0-85083072915-
dc.description.journalClass1-
dc.description.isOpenAccessN-
dc.type.docTypeArticle-
dc.subject.keywordPlusFREE-ELECTRON LASER-
dc.subject.keywordPlusDIFFRACTION-
dc.subject.keywordAuthorhigh-throughput microcrystal delivery-
dc.subject.keywordAuthorHT-MCD-
dc.subject.keywordAuthormicrocrystal delivery systems-
dc.subject.keywordAuthorserial femtosecond crystallography-
dc.subject.keywordAuthorX-ray free-electron lasers-
dc.subject.keywordAuthorXFELs-

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이종람LEE, JONG LAM
Dept of Materials Science & Enginrg
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