Vertical focusing and cell ordering in a microchannel via viscoelasticity: Applications for cell monitoring using a digital holographic microscopy
SCIE
SCOPUS
- Title
- Vertical focusing and cell ordering in a microchannel via viscoelasticity: Applications for cell monitoring using a digital holographic microscopy
- Authors
- Seo, KW; Ha, YR; Lee, SJ
- Date Issued
- 2014-05-26
- Publisher
- AMER INST PHYSICS
- Abstract
- We demonstrate sheath-free vertical concentration and positioning of cells induced by fluid viscoelasticity in a rectangular channel. The high uniformity in depth position and the reduction in cell overlap eliminate out-of-focus blurring and increase detection sensitivity. Additionally, orientational ordering of red blood cells improves the monitoring and counting performance of an optical imaging system. As a proof of concept of vertical focusing and cell ordering, we demonstrate counting and monitoring of red blood cells flowing in a microchannel using phase-contrast holographic microscopy for quantitative phase imaging. (C) 2014 AIP Publishing LLC.
- URI
- https://oasis.postech.ac.kr/handle/2014.oak/9790
- DOI
- 10.1063/1.4880615
- ISSN
- 0003-6951
- Article Type
- Article
- Citation
- APPLIED PHYSICS LETTERS, vol. 104, no. 21, page. 213702, 2014-05-26
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