Synthesis of Branched Alkylboronates by Copper-Catalyzed Allylic Substitution Reactions of Allylic Chlorides with 1,1-Diborylalkanes
SCOPUS
- Title
- Synthesis of Branched Alkylboronates by Copper-Catalyzed Allylic Substitution Reactions of Allylic Chlorides with 1,1-Diborylalkanes
- Authors
- Junghoon Kim; Sangwoo Park; Jinyoung Park; Cho, SH
- Date Issued
- 2016-01
- Publisher
- Wiley
- Abstract
- Reported herein is a copper-catalyzed S(N)2'-selective allylic substitution reaction using readily accessible allylic chlorides and 1,1-diborylalkanes, a reaction which proceeds with chemoselective C-B bond activation of the 1,1-diborylalkanes. In the presence of a catalytic amount of [Cu(IMes) Cl] [IMes=1,3-bis(2,4,6-trimethylphenyl) imidazole-2-ylidene] and LiOtBu as a base, a range of primary and secondary allylic chlorides undergo the S(N)2'-selective allylic substitution reaction to produce branched alkylboronates. The synthetic utilities of the obtained alkylboronates are also presented.
- URI
- https://oasis.postech.ac.kr/handle/2014.oak/36497
- DOI
- 10.1002/ANIE.201509840
- ISSN
- 1433-7851
- Article Type
- Article
- Citation
- Angewandte Chemie International Edition, vol. 55, no. 4, page. 1498 - 1501, 2016-01
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- There are no files associated with this item.
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