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Thermal conductivity of biological cells at cellular level and correlation with disease state SCIE SCOPUS

Title
Thermal conductivity of biological cells at cellular level and correlation with disease state
Authors
Park, BKWoo, YJeong, DPark, JChoi, TYSimmons, DPHa, JKim, D
Date Issued
2016-06-14
Publisher
AIP Publishing
Abstract
This paper reports the thermal conductivity k of matched pair cell lines: two pairs of a normal and a cancer cell, one pair of a primary and metastatic cell. The 3 omega method with a nanoscale thermal sensor was used to measure k at the single-cell level. To observe the difference in k between normal and cancer cells, the measurements were conducted for Hs 578Bst/Hs 578T (human breast cells) and TE 353.Sk/TE 354. T (human skin cells). Then k of WM-115/WM-266-4, a primary and metastatic pair of human skin cell, was measured to find the effect of disease progression on k. The measured k data for normal and disease cell samples show statistically meaningful differences. In all cases, k decreased as the disease progressed. This work shows that thermal-analysis schemes, such as the 3 omega method, have a potential to detect diseases at the cell level. Published by AIP Publishing.
URI
https://oasis.postech.ac.kr/handle/2014.oak/36427
DOI
10.1063/1.4953679
ISSN
0021-8979
Article Type
Article
Citation
Journal of Applied Physics, vol. 119, no. 22, page. 224701, 2016-06-14
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박재성PARK, JAE SUNG
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