Thermal conductivity of biological cells at cellular level and correlation with disease state
SCIE
SCOPUS
- Title
- Thermal conductivity of biological cells at cellular level and correlation with disease state
- Authors
- Park, BK; Woo, Y; Jeong, D; Park, J; Choi, TY; Simmons, DP; Ha, J; Kim, D
- Date Issued
- 2016-06-14
- Publisher
- AIP Publishing
- Abstract
- This paper reports the thermal conductivity k of matched pair cell lines: two pairs of a normal and a cancer cell, one pair of a primary and metastatic cell. The 3 omega method with a nanoscale thermal sensor was used to measure k at the single-cell level. To observe the difference in k between normal and cancer cells, the measurements were conducted for Hs 578Bst/Hs 578T (human breast cells) and TE 353.Sk/TE 354. T (human skin cells). Then k of WM-115/WM-266-4, a primary and metastatic pair of human skin cell, was measured to find the effect of disease progression on k. The measured k data for normal and disease cell samples show statistically meaningful differences. In all cases, k decreased as the disease progressed. This work shows that thermal-analysis schemes, such as the 3 omega method, have a potential to detect diseases at the cell level. Published by AIP Publishing.
- URI
- https://oasis.postech.ac.kr/handle/2014.oak/36427
- DOI
- 10.1063/1.4953679
- ISSN
- 0021-8979
- Article Type
- Article
- Citation
- Journal of Applied Physics, vol. 119, no. 22, page. 224701, 2016-06-14
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- There are no files associated with this item.
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