Development of a hybrid scaffold and a bioreactor for cartilage regeneration
SCIE
SCOPUS
- Title
- Development of a hybrid scaffold and a bioreactor for cartilage regeneration
- Authors
- Seung-Jae Lee; In Hwan Lee; Jeong Hun Park; So-Jung Gwak; Jong-Won Rhie; Cho, DW; Tae Jo Ko; Kim, DS
- Date Issued
- 2009-10
- Publisher
- SCIENCE PRESS
- Abstract
- We developed a hybrid scaffold and a bioreactor for cartilage regeneration. The hybrid scaffold was developed as combination of two components: a biodegradable framework and hydrogel-containing chondrocytes. We performed the MTT cell proliferation assay to compare the proliferation and viability of chondrocytes on three types of scaffolds: an alginate gel, the hybrid scaffold, and an alginate sponge. Cells were encapsulated in 2% agarose gel. The bioreactor consisted of a circulation system and a compression system. We performed dynamic cell culture on these agarose gels in the bioreactor for 3 days.
- Keywords
- cartilage; scaffold; bioreactor; alginate; agarose; CARBONATE-BASED PREPOLYMERS
- URI
- https://oasis.postech.ac.kr/handle/2014.oak/27832
- DOI
- 10.1007/s11434-009-0602-8
- ISSN
- 1001-6538
- Article Type
- Article
- Citation
- CHINESE SCIENCE BULLETIN, vol. 54, no. 19, page. 3608 - 3612, 2009-10
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