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  Division of Advanced Materials Science (AMS) (첨단재료과학부) 1. Journal Papers

 

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Cited 60 time in webofscience Cited 64 time in scopus
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dc.contributor.authorLee, YS-
dc.contributor.authorPark, SM-
dc.contributor.authorKim, HM-
dc.contributor.authorPark, SK-
dc.contributor.authorLee, K-
dc.contributor.authorLee, CW-
dc.contributor.authorKim, BH-
dc.date.accessioned2016-04-01T03:09:16Z-
dc.date.available2016-04-01T03:09:16Z-
dc.date.created2010-04-21-
dc.date.issued2009-08-15-
dc.identifier.issn0960-894X-
dc.identifier.other2009-OAK-0000020622-
dc.identifier.urihttps://oasis.postech.ac.kr/handle/2014.oak/26323-
dc.description.abstractWe describe (i) a simple method for the synthesis of C5-modified nucleosides from 5-iodo-2'deoxyuridine and (ii) their activity against six types of human cancer cell lines (HCT15, MM231, NCI-H23, NUGC-3, PC-3, ACHN). We generated nitrile oxides in situ from oximes using a commercial bleaching agent; their cycloadditions with 5-ethynyl-2'-deoxyuridine yielded isoxazole derivatives possessing activity against the cancer cell lines. We synthesized several azides from benzylic bromides and their click reactions with 5-ethynyl-2'-deoxyuridine provided triazole derivatives. (C) 2009 Elsevier Ltd. All rights reserved.-
dc.description.statementofresponsibilityX-
dc.languageEnglish-
dc.publisherPERGAMON-ELSEVIER SCIENCE LTD-
dc.relation.isPartOfBIOORGANIC & MEDICINAL CHEMISTRY LETTERS-
dc.subjectAnticancer-
dc.subjectNucleoside-
dc.subjectTriazole-
dc.subjectIsoxazole-
dc.subjectCycloaddition-
dc.subjectCANCER-
dc.subjectIDENTIFICATION-
dc.subjectCYTOTOXICITY-
dc.subjectCLOFARABINE-
dc.subjectISOXAZOLE-
dc.subjectANALOGS-
dc.subjectDESIGN-
dc.subjectCELLS-
dc.titleC5-Modified nucleosides exhibiting anticancer activity-
dc.typeArticle-
dc.contributor.college융합생명공학부-
dc.identifier.doi10.1016/J.BMCL.2009.06.072-
dc.author.googleLee, YS-
dc.author.googlePark, SM-
dc.author.googleKim, HM-
dc.author.googlePark, SK-
dc.author.googleLee, K-
dc.author.googleLee, CW-
dc.author.googleKim, BH-
dc.relation.volume19-
dc.relation.issue16-
dc.relation.startpage4688-
dc.relation.lastpage4691-
dc.contributor.id10142056-
dc.relation.journalBIOORGANIC & MEDICINAL CHEMISTRY LETTERS-
dc.relation.indexSCI급, SCOPUS 등재논문-
dc.relation.sciSCI-
dc.collections.nameJournal Papers-
dc.type.rimsART-
dc.identifier.bibliographicCitationBIOORGANIC & MEDICINAL CHEMISTRY LETTERS, v.19, no.16, pp.4688 - 4691-
dc.identifier.wosid000268358800034-
dc.date.tcdate2019-02-01-
dc.citation.endPage4691-
dc.citation.number16-
dc.citation.startPage4688-
dc.citation.titleBIOORGANIC & MEDICINAL CHEMISTRY LETTERS-
dc.citation.volume19-
dc.contributor.affiliatedAuthorKim, BH-
dc.identifier.scopusid2-s2.0-67749119952-
dc.description.journalClass1-
dc.description.journalClass1-
dc.description.wostc50-
dc.description.scptc52*
dc.date.scptcdate2018-05-121*
dc.type.docTypeArticle-
dc.subject.keywordPlusCANCER-
dc.subject.keywordPlusIDENTIFICATION-
dc.subject.keywordPlusCYTOTOXICITY-
dc.subject.keywordPlusCLOFARABINE-
dc.subject.keywordPlusISOXAZOLE-
dc.subject.keywordPlusANALOGS-
dc.subject.keywordPlusDESIGN-
dc.subject.keywordPlusCELLS-
dc.subject.keywordAuthorAnticancer-
dc.subject.keywordAuthorNucleoside-
dc.subject.keywordAuthorTriazole-
dc.subject.keywordAuthorIsoxazole-
dc.subject.keywordAuthorCycloaddition-
dc.relation.journalWebOfScienceCategoryChemistry, Medicinal-
dc.relation.journalWebOfScienceCategoryChemistry, Organic-
dc.description.journalRegisteredClassscie-
dc.description.journalRegisteredClassscopus-
dc.relation.journalResearchAreaPharmacology & Pharmacy-
dc.relation.journalResearchAreaChemistry-
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김병현KIM, BYEANG HYEAN
Div of Advanced Materials Science
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