Open Access System for Information Sharing

Login Library

 

Article
Cited 0 time in webofscience Cited 0 time in scopus
Metadata Downloads

Chemoenzymatic Dynamic Kinetic Resolution of Alcohols and Amines

Title
Chemoenzymatic Dynamic Kinetic Resolution of Alcohols and Amines
Authors
Lee, JHHan, KKim, MJPark, J김만주
Date Issued
2010-02
Publisher
Wiley-VCH
Abstract
Dynamic kinetic resolution (DKR) is an attractive process for the transformation of racemic mixtures into optically active compounds. For successful DKR, efficient racemization is required while the kinetic resolution is proceeding, This Micro-review mainly summarizes the recent developments in the DKR of alcohols and amines, based on metal-catalyzed racemization and enzymatic acylation in a single reaction vessel. Related reactions involving precursors of alcohols and amines Such as ketones, enol acetates, and ketoximes are also described. Reaction conditions are arranged according to racemization catalysts, and substrates employed in the DKR are tabulated. Suggested mechanisms for metal-catalyzed racemizations are also summarized.
Keywords
Dynamic kinetic resolution; Transesterification; Enzymes; Alcohols; Amines; RUTHENIUM-CATALYZED RACEMIZATION; ASYMMETRIC TRANSFER HYDROGENATION; ONE-POT SYNTHESIS; ENANTIOMERICALLY PURE AMINES; ALKALINE-EARTH SUPPORTS; METAL COMBO CATALYSIS; SECONDARY ALCOHOLS; EFFICIENT ROUTE; ENZYMATIC RESOLUTION; ROOM-TEMPERATURE
URI
https://oasis.postech.ac.kr/handle/2014.oak/24997
DOI
10.1002/EJOC.200900935
ISSN
1434-193X
Article Type
Article
Files in This Item:
There are no files associated with this item.

qr_code

  • mendeley

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

Views & Downloads

Browse