Accumulation of phosphorylated repressor for gibberellin signaling in an F-box mutant
SCIE
SCOPUS
- Title
- Accumulation of phosphorylated repressor for gibberellin signaling in an F-box mutant
- Authors
- Sasaki, A; Itoh, H; Gomi, K; Ueguchi-Tanaka, M; Ishiyama, K; Kobayashi, M; Jeong, DH; An, G; Kitano, H; Ashikari, M; Matsuoka, M
- Date Issued
- 2003-03-21
- Publisher
- AMER ASSOC ADVANCEMENT SCIENCE
- Abstract
- Gibberellin (GA) regulates growth and development in plants. We isolated and characterized a rice GA-insensitive dwarf mutant, gid2. The GID2 gene encodes a putative F-box protein, which interacted with the rice Skp1 homolog in a yeast two-hybrid assay. In gid2, a repressor for GA signaling, SLR1, was highly accumulated in a phosphorylated form and GA increased its concentration, whereas SLR1 was rapidly degraded by GA through ubiquitination in the wild type. We conclude that GID2 is a positive regulator of GA signaling and that regulated degradation of SLR1 is initiated through GA-dependent phosphorylation and finalized by an SCFGID2-proteasome pathway.
- Keywords
- UBIQUITIN-LIGASE COMPLEX; GREEN-REVOLUTION; RESPONSE MUTANT; GENE; ARABIDOPSIS; RICE; PATHWAY; RGA; DEGRADATION; EXPRESSION
- URI
- https://oasis.postech.ac.kr/handle/2014.oak/18629
- DOI
- 10.1126/science.1081077
- ISSN
- 0036-8075
- Article Type
- Article
- Citation
- SCIENCE, vol. 299, no. 5614, page. 1896 - 1898, 2003-03-21
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- There are no files associated with this item.
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