Proteomic analysis of outer membrane vesicles derived from Pseudomonas aeruginosa
SCIE
SCOPUS
- Title
- Proteomic analysis of outer membrane vesicles derived from Pseudomonas aeruginosa
- Authors
- Choi, DS; Kim, DK; Choi, SJ; Lee, J; Choi, JP; Rho, S; Park, SH; Kim, YK; Hwang, D; Gho, YS
- Date Issued
- 2011-08
- Publisher
- WILEY-BLACKWELL
- Abstract
- Pseudomonas aeruginosa, an opportunistic human bacterial pathogen, constitutively secretes outer membrane vesicles (OMVs) into the extracellular milieu. Although recent progress has revealed that OMVs are essential for pathogenesis of P. aeruginosa, their proteins have not been comprehensively analyzed so far. In this study, we identified 338 vesicular proteins with high confidence by five separate LC-MS/MS analyses. This global proteome profile provides a basis for future studies to elucidate the pathological functions of OMVs from P. aeruginosa.
- Keywords
- Microbiology; Outer membrane vesicles; Pseudomonas aeruginosa; Vaccine; GRAM-NEGATIVE BACTERIA; INNATE IMMUNE-RESPONSE; CYSTIC-FIBROSIS; SAMPLE PREPARATION; MASS-SPECTROMETRY; BETA-LACTAMASE; PROTEINS; IDENTIFICATIONS; PURIFICATION; INFECTIONS
- URI
- https://oasis.postech.ac.kr/handle/2014.oak/17059
- DOI
- 10.1002/PMIC.201000212
- ISSN
- 1615-9853
- Article Type
- Article
- Citation
- PROTEOMICS, vol. 11, no. 16, page. 3424 - 3429, 2011-08
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- There are no files associated with this item.
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