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Multifunctional microbubbles and nanobubbles for photoacoustic and ultrasound imaging SCIE SCOPUS

Title
Multifunctional microbubbles and nanobubbles for photoacoustic and ultrasound imaging
Authors
Kim, CQin, RGXu, JSWang, LVXu, R
Date Issued
2010-01
Publisher
SPIE
Abstract
We develop a novel dual-modal contrast agent-encapsulated-ink poly(lactic-co-glycolic acid) (PLGA) microbubbles and nanobubbles-for photoacoustic and ultrasound imaging. Soft gelatin phantoms with embedded tumor simulators of encapsulated-ink PLGA microbubbles and nanobubbles in various concentrations are clearly shown in both photoacoustic and ultrasound images. In addition, using photoacoustic imaging, we successfully image the samples positioned below 1.8-cm-thick chicken breast tissues. Potentially, simultaneous photoacoustic and ultrasound imaging enhanced by encapsulated-dye PLGA microbubbles or nanobubbles can be a valuable tool for intraoperative assessment of tumor boundaries and therapeutic margins. (C) 2010 Society of Photo-Optical Instrumentation Engineers. [DOI: 10.1117/1.3302808]
URI
https://oasis.postech.ac.kr/handle/2014.oak/10670
DOI
10.1117/1.3302808
ISSN
1083-3668
Article Type
Article
Citation
JOURNAL OF BIOMEDICAL OPTICS, vol. 15, no. 1, 2010-01
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김철홍KIM, CHULHONG
Dept of Electrical Enginrg
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