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Cited 20 time in webofscience Cited 22 time in scopus
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dc.contributor.authorYum, JS-
dc.contributor.authorAhn, BC-
dc.contributor.authorJo, HJ-
dc.contributor.authorKim, DY-
dc.contributor.authorKim, KH-
dc.contributor.authorKim, HS-
dc.contributor.authorSung, YC-
dc.contributor.authorYoon, J-
dc.contributor.authorMorrey, J-
dc.contributor.authorMoon, HM-
dc.date.accessioned2015-06-25T01:47:45Z-
dc.date.available2015-06-25T01:47:45Z-
dc.date.created2013-02-27-
dc.date.issued2012-02-
dc.identifier.issn1556-6811-
dc.identifier.other2015-OAK-0000026594en_US
dc.identifier.urihttps://oasis.postech.ac.kr/handle/2014.oak/10065-
dc.description.abstractA hepatitis B virus (HBV) vaccine has been developed using a new adjuvant and HBV surface antigens produced from a CHO cell line. The purified HBV surface antigens are composed of L protein, Mprotein, and S protein in a mixture of 20- and 40-nm-diameter particles and filamentous forms. This HBV surface antigen, formulated with L-pampo, a proprietary adjuvant, induced 10 times more antibody than the same antigen with alum and was capable of inducing strong immune responses in three different HBV transgenic mice. In spite of the presence of a large amount of HBV antigen in the blood, no antibody against HBV surface antigen was normally detected in these transgenic mice. After immunization, the HBV antigen was also cleared from the blood.-
dc.description.statementofresponsibilityopenen_US
dc.languageEnglish-
dc.publisherAmerican society for microbiology-
dc.relation.isPartOfCLINICAL AND VACCINE IMMUNOLOGY-
dc.rightsBY_NC_NDen_US
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/2.0/kren_US
dc.titleUse of pre S containing Hepatitis B virus surface antigens and a powerful adjuvant to develop an immune therapy for Hepatitis B virus chronic infection.-
dc.typeArticle-
dc.contributor.college융합생명공학부en_US
dc.identifier.doi10.1128/CVI.05355-11-
dc.author.googleYum, JSen_US
dc.author.googleAhn, BCen_US
dc.author.googleMoon, HMen_US
dc.author.googleMorrey, Jen_US
dc.author.googleYoon, Jen_US
dc.author.googleSung, YCen_US
dc.author.googleKim, HSen_US
dc.author.googleKim, KHen_US
dc.author.googleKim, DYen_US
dc.author.googleJo, HJen_US
dc.relation.volume19en_US
dc.relation.issue2en_US
dc.relation.startpage120en_US
dc.relation.lastpage127en_US
dc.contributor.id10053752en_US
dc.relation.journalCLINICAL AND VACCINE IMMUNOLOGYen_US
dc.relation.indexSCI급, SCOPUS 등재논문en_US
dc.relation.sciSCIen_US
dc.collections.nameJournal Papersen_US
dc.type.rimsART-
dc.identifier.bibliographicCitationCLINICAL AND VACCINE IMMUNOLOGY, v.19, no.2, pp.120 - 127-
dc.identifier.wosid000300044800002-
dc.date.tcdate2019-01-01-
dc.citation.endPage127-
dc.citation.number2-
dc.citation.startPage120-
dc.citation.titleCLINICAL AND VACCINE IMMUNOLOGY-
dc.citation.volume19-
dc.contributor.affiliatedAuthorSung, YC-
dc.identifier.scopusid2-s2.0-84863075697-
dc.description.journalClass1-
dc.description.journalClass1-
dc.description.wostc7-
dc.type.docTypeArticle-
dc.subject.keywordPlusSUBCLASS RESPONSES-
dc.subject.keywordPlusT-CELL-
dc.subject.keywordPlusVACCINE-
dc.subject.keywordPlusMICE-
dc.subject.keywordPlusIMMUNOGENICITY-
dc.subject.keywordPlusANTIBODIES-
dc.subject.keywordPlusIGG-
dc.subject.keywordPlusIMMUNIZATION-
dc.subject.keywordPlusPROTECTION-
dc.subject.keywordPlusSECRETION-
dc.relation.journalWebOfScienceCategoryImmunology-
dc.relation.journalWebOfScienceCategoryInfectious Diseases-
dc.relation.journalWebOfScienceCategoryMicrobiology-
dc.description.journalRegisteredClassscie-
dc.description.journalRegisteredClassscopus-
dc.relation.journalResearchAreaImmunology-
dc.relation.journalResearchAreaInfectious Diseases-
dc.relation.journalResearchAreaMicrobiology-

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성영철SUNG, YOUNG CHUL
Dept of Life Sciences
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