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dc.contributor.authorLEE, SANG JAE-
dc.date.available2019-10-22T09:10:03Z-
dc.date.created2019-10-17-
dc.date.issued2019-11-01-
dc.identifier.urihttp://oasis.postech.ac.kr/handle/2014.oak/99777-
dc.description.abstractBecause three-dimensional protein structure can provide important information, structure-based drug discovery and development possibly leads a way for researchers to find a drug lead using rational approaches. Here, I will show some of research results that shows the process of SBDD, including development of antibiotics, anticancer agent, and anti-hypercholesterolemia, as well as consideration in choosing a method for drug lead discovery and evaluation of the drug leads. In addition, I will introduce a kind of ideal way to perform SBDD using XFEL (SFX program). By utilizing XFEL, we can get a protein structure at room temperature without radiation damage, leading us to get a better scaffold at the initial stage of drug discovery program.-
dc.languageEnglish-
dc.publisher한국결정학회-
dc.relation.ispartof2019 한국결정학회 학술대회-
dc.titleStructure-guided drug discovery and development-
dc.typeConference-
dc.type.rimsCONF-
dc.identifier.bibliographicCitation2019 한국결정학회 학술대회-
dc.citation.conferenceDate2019-11-01-
dc.citation.conferencePlaceKO-
dc.citation.conferencePlaceUNIST-
dc.citation.title2019 한국결정학회 학술대회-
dc.contributor.affiliatedAuthorLEE, SANG JAE-
dc.description.journalClass2-

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