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Cited 8 time in webofscience Cited 8 time in scopus
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Development of pH-Responsive BODIPY Probes for Staining Late Endosome in Live Cells

Title
Development of pH-Responsive BODIPY Probes for Staining Late Endosome in Live Cells
Authors
Miao, FangUchinomiya, ShoheiNi, YongChang, Young-TaeWu, Jishan
POSTECH Authors
Chang, Young-Tae
Date Issued
Nov-2016
Publisher
WILEY-V C H VERLAG GMBH
Abstract
Reported is a new fluorescent probe based on boron-dipyrromethene dye (BODIPY) for late endosome staining in live cells. Among the 14 pH-responsive BODIPY-based far-red/near-infrared dyes used, it was found that a (4-methyl-1-piperazinyl)phenyl-substituted BODIPY could stain late endosomes in three different cell lines. This BODIPY dye was applicable for measurement of the fusion time of late endosomes and lysosomes, thereby demonstrating the utility of this dye for functional analyses of late endosomes in live cells.
Keywords
FLUORESCENT-PROBE; LYSOSOMAL PH; LIVING CELLS; DYES; ENDOCYTOSIS; DISEASE; VALUES; ACID; RED
URI
http://oasis.postech.ac.kr/handle/2014.oak/50394
DOI
10.1002/cplu.201600249
ISSN
2192-6506
Article Type
Article
Citation
ChemPlusChem, vol. 81, no. 11, page. 1209 - 1215, 2016-11
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 CHANG, YOUNG TAE
Dept of Chemistry
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