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Syntheses of D- and L-myo-inositol 1,2,4,5-tetrakisphosphate and stereoselectivity of the I(1,4,5)P-3 receptor binding

Title
Syntheses of D- and L-myo-inositol 1,2,4,5-tetrakisphosphate and stereoselectivity of the I(1,4,5)P-3 receptor binding
Authors
Chung, SKShin, BGCHANG, YOUNG TAESuh, BCKim, KT
POSTECH Authors
CHANG, YOUNG TAEKim, KT
Date Issued
Jan-1998
Publisher
PERGAMON-ELSEVIER SCIENCE LTD
Abstract
D- and L-myo-Inositol 1,2,4,5-tetrakisphosphate [D- & L-I(1,2,4,5)P-4], which are analogues of D-myo-Inositol 1,4,5-trisphosphate [D-I(1,4,5)P-3], a calcium mobilizing second messenger, were synthesized via resolution of the camphanate ester of a myo-inositol derivative, and the binding affinities to I(1,4,5)P-3 receptor were measured. (C) 1998 Elsevier Science Ltd. All rights reserved.
Keywords
MYOINOSITOL 1,4,5-TRISPHOSPHATE; CALCIUM; ANALOGS; CELLS; TETRAKISPHOSPHATES; TRISPHOSPHATE; MOBILIZATION; DERIVATIVES
URI
http://oasis.postech.ac.kr/handle/2014.oak/20834
DOI
10.1016/S0960-894X(98)00081-X
ISSN
0960-894X
Article Type
Article
Citation
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 8, no. 6, page. 659 - 662, 1998-01
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 KIM, KYONG TAI
Div of Integrative Biosci & Biotech
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