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Cited 209 time in webofscience Cited 242 time in scopus
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dc.contributor.authorSong, WYko
dc.contributor.authorSohn, EJko
dc.contributor.authorMartinoia, Eko
dc.contributor.authorLee, YJko
dc.contributor.authorYang, YYko
dc.contributor.authorJasinski, Mko
dc.contributor.authorForestier, Cko
dc.contributor.authorHwang, Iko
dc.contributor.authorLee, Yko
dc.date.available2016-03-31T12:47:57Z-
dc.date.created2009-08-18-
dc.date.issued2003-01-
dc.identifier.citationNATURE BIOTECHNOLOGY, v.21, no.8, pp.914 - 919-
dc.identifier.issn1087-0156-
dc.identifier.other2003-OAK-0000003561-
dc.identifier.urihttp://oasis.postech.ac.kr/handle/2014.oak/18425-
dc.description.abstractWe have studied the utility of the yeast protein YCF1, which detoxifies cadmium by transporting it into vacuoles, for the remediation of lead and cadmium contamination. We found that the yeast YCF1-deletion mutant DTY167 was hypersensitive to Pb(II) as compared with wild-type yeast. DTY167 cells overexpressing YCF1 were more resistant to Pb( II) and Cd( II) than were wild-type cells, and accumulated more lead and cadmium. Analysis of transgenic Arabidopsis thaliana plants overexpressing YCF1 showed that YCF1 is functionally active and that the plants have enhanced tolerance of Pb( II) and Cd( II) and accumulated greater amounts of these metals. These results suggest that transgenic plants expressing YCF1 may be useful for phytoremediation of lead and cadmium.-
dc.description.statementofresponsibilityX-
dc.languageEnglish-
dc.publisherNATURE PUBLISHING GROUP-
dc.subjectRESISTANCE-ASSOCIATED PROTEIN-
dc.subjectSACCHAROMYCES-CEREVISIAE-
dc.subjectARABIDOPSIS-THALIANA-
dc.subjectINDIAN MUSTARD-
dc.subjectYEAST-
dc.subjectGLUTATHIONE-
dc.subjectTRANSPORT-
dc.subjectGENE-
dc.subjectPHYTOREMEDIATION-
dc.subjectDETOXIFICATION-
dc.titleEngineering tolerance and accumulation of lead and cadmium in transgenic plants-
dc.typeArticle-
dc.contributor.college생명과학과-
dc.identifier.doi10.1038/NBT850-
dc.author.googleSong, WY-
dc.author.googleSohn, EJ-
dc.author.googleMartinoia, E-
dc.author.googleLee, YJ-
dc.author.googleYang, YY-
dc.author.googleJasinski, M-
dc.author.googleForestier, C-
dc.author.googleHwang, I-
dc.author.googleLee, Y-
dc.relation.volume21-
dc.relation.issue8-
dc.relation.startpage914-
dc.relation.lastpage919-
dc.contributor.id10078446-
dc.publisher.locationUS-
dc.relation.journalNATURE BIOTECHNOLOGY-
dc.relation.indexSCI급, SCOPUS 등재논문-
dc.relation.sciSCI-
dc.collections.nameJournal Papers-
dc.type.rimsART-
dc.contributor.localauthorHwang, I-
dc.contributor.localauthorLee, Y-
dc.contributor.nonIdAuthorSong, WY-
dc.contributor.nonIdAuthorSohn, EJ-
dc.contributor.nonIdAuthorMartinoia, E-
dc.contributor.nonIdAuthorLee, YJ-
dc.contributor.nonIdAuthorYang, YY-
dc.contributor.nonIdAuthorJasinski, M-
dc.contributor.nonIdAuthorForestier, C-
dc.identifier.wosid000184484600035-
dc.date.tcdate2019-01-01-
dc.citation.endPage919-
dc.citation.number8-
dc.citation.startPage914-
dc.citation.titleNATURE BIOTECHNOLOGY-
dc.citation.volume21-
dc.identifier.scopusid2-s2.0-0043208901-
dc.description.journalClass1-
dc.description.wostc205-
dc.description.scptc224*
dc.date.scptcdate2018-05-121*

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