Open Access System for Information Sharing

Login Library

 

Article
Cited 0 time in webofscience Cited 0 time in scopus
Metadata Downloads

Intermolecular interactions of chitosan: Degree of acetylation and molecular weight

Title
Intermolecular interactions of chitosan: Degree of acetylation and molecular weight
Authors
Lim, ChanoongHWANG, DONG SOOLee, Dong Woog
Date Issued
May-2021
Publisher
Pergamon Press Ltd.
Abstract
The degree of acetylation (DA), which determines as the molar proportion of N-acetyl-D-glucosamine units on chitosan, characterizes the physical, chemical, and biological properties of chitosan. Thus, DA can be a critical factor in the utilization of chitosan. Nevertheless, quantitative studies on the molecular interactions of chitosan as a function of DA are lacking. Here, we directly measured the molecular interaction (adhesion and cohesion) of molecularly thin chitosan films, dependent on the molecular weight and DA, using a surface forces apparatus. Using low molecular weight (LMW, ∼5 kDa) and high molecular weight (HMW, ∼135 kDa) chitosan, we obtained several DA ranges through a reacetylation method. The interactions of LMW chitosan were greatly influenced by the intrinsic charge of the chitosan units, whereas for HMW chitosan, chain flexibility was found to be the major factor affecting molecular interaction Taken together, our comprehensive data provides a holistic understanding of the interaction mechanism of chitosan.
URI
http://oasis.postech.ac.kr/handle/2014.oak/105084
ISSN
0144-8617
Article Type
Article
Citation
Carbohydrate Polymers, vol. 259, page. 117782, 2021-05
Files in This Item:
There are no files associated with this item.

qr_code

  • mendeley

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

Related Researcher

Researcher

황동수HWANG, DONG SOO
Div of Environmental Science & Enginrg
Read more

Views & Downloads

Browse