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RNA nanotechnology in synthetic biology

Title
RNA nanotechnology in synthetic biology
Authors
KIM, JONGMINFRANCO, ELISA
Date Issued
Jun-2020
Publisher
CURRENT BIOLOGY LTD
Abstract
We review recent advances in the design and expression of synthetic RNA sequences inside cells, to regulate gene expression and to achieve spatial localization of components. We focus on approaches that exploit the programmability of the secondary and tertiary structure of RNA to build scalable and modular devices that fold spontaneously and have the capacity to respond to environmental inputs.
Keywords
MAMMALIAN-CELLS; GENE-EXPRESSION; GUIDE RNAS; CRISPR; REGULATORS; DESIGN; COMPUTATION; SCAFFOLDS; BACTERIAL; STRATEGY
URI
http://oasis.postech.ac.kr/handle/2014.oak/100875
ISSN
0958-1669
Article Type
Article
Citation
CURRENT OPINION IN BIOTECHNOLOGY, vol. 63, page. 135 - 141, 2020-06
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